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MilliporeSigma

1.03583

SAFC

Parteck® SI 150 (Sorbitol)

EMPROVE® ESSENTIAL, Ph. Eur., BP, JP, NF, JSFA, E 420

Synonym(s):

Parteck® Sorbitol, D-Glucitol

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About This Item

Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
Molecular Weight:
182.17
MDL number:
UNSPSC Code:
12352201
E Number:
E420

$1,350.00


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Agency

BP
JP
JSFA
NF
Ph. Eur.

Quality Level

product line

EMPROVE® ESSENTIAL

form

fine powder

autoignition temp.

420 °C

particle size

(see specification)

pH

6-7 (20 °C, 100 g/L in H2O)

mp

94-96 °C

transition temp

flash point >100 °C

solubility

2350 g/L

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This Item
28-4680SX0995211982
Solvent solvent for volumetric Karl Fischer titration with two component reagents Aquastar®

1.88015

Solvent

technique(s)

Karl-Fischer titration: suitable

technique(s)

-

technique(s)

-

technique(s)

-

format

two component solution

format

-

format

-

format

-

product line

Aquastar®

product line

-

product line

-

product line

-

form

liquid

form

liquid

form

liquid

form

powder

transition temp

flash point 11 °C (Methanol)

transition temp

-

transition temp

flash point 38 °C

transition temp

-

General description

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Parteck® SI excipient is a directly compressible sorbitol which combines excellent tableting behavior, resulting in very robust and shiny tablets, with a pleasant mouthfeel and taste. The unique and large surface area allows for a fast disintegration and dissolution, even at high tablet hardnesses and supports a good content uniformity of low dose API formulations. Parteck® SI excipient comes in a variety of particle sizes and qualities to meet the needs of a very wide range of applications.

Features and Benefits

  • Excellent direct compression properties
  • High dilution and adsorption capacity
  • Larger and highly structured surface area
  • Low hygroscopicity
  • Low amount of reducing sugars

Storage and Stability

Storage temperature: no restrictions.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


  • What is the Emprove® Program?

    The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials. Four document types are included with an Emprove® Program subscription:

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    Quality Management Dossier (Open Access)

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    Quality Management Dossier (Open Access)

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    Operational Excellence Dossier

    Available by subscription or for a fee

    Operational Excellence Dossier

    Available by subscription or for a fee

    Learn more about the benefits an Emprove® Program subscription can provide
    Why are these documents unavailable?
    Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

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    Articles

    3D printing can overcome challenges during formulation development, with a focus on enhancing API bioavailability in solid dispersions. Find out how in this technical article.

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