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MilliporeSigma

1.07583

SAFC

Parteck® SI 150 (Sorbitol)

EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, JP, NF, JSFA, E 420

Pharma Manufacturing

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Synonym(s):
Parteck® Sorbitol
Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
Molecular Weight:
182.17
MDL number:
UNSPSC Code:
12352201
E Number:
E 420
EC Index Number:
200-061-5

agency

BP
ChP
JP
JSFA
NF
Ph. Eur.

Quality Level

product line

EMPROVE® ESSENTIAL

form

fine powder

mol wt

182.17 g/mol

application(s)

pharmaceutical
solid formulation

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2

InChI key

FBPFZTCFMRRESA-UHFFFAOYSA-N

General description

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Parteck® SI excipient is a directly compressible sorbitol which combines excellent tableting behavior, resulting in very robust and shiny tablets, with a pleasant mouthfeel and taste. The unique and large surface area allows for a fast disintegration and dissolution, even at high tablet hardnesses and supports a good content uniformity of low dose API formulations.
Parteck® SI excipient comes in a variety of particle sizes and qualities to meet the needs of a very wide range of applications. This article′s specifications are in compliance with ChP requirements.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Articles

This article describes the use of excipients to help address API stability issues.

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