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130532

Sigma-Aldrich

5,7-Dichloro-8-hydroxy-2-methylquinoline

98%

Synonym(s):

5,7-Dichloro-2-methyl-8-quinolinol, 5,7-Dichloro-8-hydroxyquinaldine, 5,7-Dichloro-8-quinaldinol, BCM

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About This Item

Empirical Formula (Hill Notation):
C10H7Cl2NO
CAS Number:
72-80-0
Molecular Weight:
228.07
Beilstein:
156683
EC Number:
200-789-3
MDL number:
MFCD00023984
UNSPSC Code:
12352100
PubChem Substance ID:
24847966
NACRES:
NA.22

Assay

98%

mp

108-112 °C (dec.) (lit.)

SMILES string

Cc1ccc2c(Cl)cc(Cl)c(O)c2n1

InChI

1S/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3

InChI key

GPTXWRGISTZRIO-UHFFFAOYSA-N

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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I Corrihons et al.
Pathologie-biologie, 39(2), 136-139 (1991-02-01)
The activity of chlorquinaldol, a derivative of hydroxy-8-quinolein used for local antisepsy, was studied against Neisseria gonorrhoeae and Chlamydia trachomatis. The weak solubility of the product and the special growth conditions of the organisms made an adaptation of the AFNOR
A double-blind comparative study to compare the efficacy of Locoid C with Tri-Adcortyl in children with infected eczema.
F O Meenan
The British journal of clinical practice, 42(5), 200-202 (1988-05-01)
T I Kaya et al.
Clinical and experimental dermatology, 34(8), e611-e613 (2009-06-06)
Incontinentia pigmenti (IP) is a rare genodermatosis caused by a mutation of nuclear factor kappa B essential modulator gene. There is no specific treatment for IP, therefore it has been claimed that there is no effective treatment to hasten resolution
[Acute renal failure after voluntary ingestion of gynecologic tablets. Beware of the excipient (boric acid)].
Y Domart et al.
Presse medicale (Paris, France : 1983), 21(3), 132-133 (1992-01-25)
V Zlatkov et al.
Akusherstvo i ginekologiia, 35(4), 49-50 (1996-01-01)
The aim of this study is the clinical testing of the vaginal wide-range, antimicrobial, quinolone--Chlorchinaldin/0,2/by POLFA, which has a strong antibacterial, antifungal, trichomonal and keratoplastic effect. The medicine was used on 43 patients with complaints of aggravated fluor. The clinical
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