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200654

Sigma-Aldrich

Ethyl cellulose

viscosity 300 cP, 5 % in toluene/ethanol 80:20(lit.), extent of labeling: 48% ethoxyl

Synonym(s):

Ethylcellulose

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23

form

granular

autoignition temp.

698 °F

concentration

48.0-49.5%

extent of labeling

48% ethoxyl

refractive index

n20/D 1.47 (lit.)

viscosity

300 cP, 5 % in toluene/ethanol 80:20(lit.)

transition temp

softening point 157 °C

density

1.14 g/mL at 25 °C (lit.)

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General description

Ethyl cellulose (EC) is a non-toxic, biocompatible, and hydrophobic polymer used for the sustained release preparation of pharmaceutical products.

Application

Ethyl cellulose can be used to prepare polymer coatings for various applications. For example, it is used to encapsulate salt hydrates for low-temperature heat storage applications.

It can be used as an efficient carrier for multiparticulate sustained drug delivery. For example, it can be used to develop polymeric microspheres for the controlled release of Ivabradine HCL (IBH).

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Dace Gao et al.
Nanoscale horizons, 5(4), 730-738 (2020-02-18)
The design and construction of 3D architectures enabled by stimuli-responsive soft materials can yield novel functionalities for next generation soft-bodied actuating devices. Apart from additive manufacturing processes, origami inspired technology offers an alternative approach to fabricate 3D actuators from planar
Ghulam Murtaza
Acta poloniae pharmaceutica, 69(1), 11-22 (2012-05-12)
Ethylcellulose (EC) based microencapsulated drug delivery systems are being extensively studied throughout the world for achieving extended drug release and protecting the core substance from degradation. The in vitro evaluation of EC microcapsules have elucidated that their particle characteristics are
Li-Ya Huang et al.
International journal of pharmaceutics, 436(1-2), 88-96 (2012-07-14)
A drug-loaded nanofiber mesh which could achieve time-engineeringed biphasic release was fabricated through sequential electrospinning. The drug to polymer ratio of each single mesh was allocated and designed before the tri-layered meshes were created. The resultant meshes had the following
Ritesh M Pabari et al.
Expert opinion on drug delivery, 9(12), 1463-1474 (2012-10-16)
To examine the potential of a novel 3-fluid nozzle spray drying technology to formulate differentiated layered microparticles (MPs) of diclofenac sodium (DFS)/ethyl cellulose (EC). DFS/EC MPs were formulated using the inner and/or outer nozzles of a novel 3-fluid nozzle and
H V Adikane et al.
Applied biochemistry and biotechnology, 169(3), 1026-1038 (2013-01-09)
The chemical modification of developed ethyl cellulose-based membrane was carried out to make it suitable for bioseparation. The different reagents were used for the modification of membrane to couple protein A (PA) to study the purification of immunoglobulin G (IgG)

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