200654
Ethyl cellulose
viscosity 300 cP, 5 % in toluene/ethanol 80:20(lit.), extent of labeling: 48% ethoxyl
Synonym(s):
Ethylcellulose
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About This Item
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form
granular
autoignition temp.
698 °F
concentration
48.0-49.5%
extent of labeling
48% ethoxyl
refractive index
n20/D 1.47 (lit.)
viscosity
300 cP, 5 % in toluene/ethanol 80:20(lit.)
transition temp
softening point 157 °C
density
1.14 g/mL at 25 °C (lit.)
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General description
Ethyl cellulose (EC) is a non-toxic, biocompatible, and hydrophobic polymer used for the sustained release preparation of pharmaceutical products.
Application
Ethyl cellulose can be used to prepare polymer coatings for various applications. For example, it is used to encapsulate salt hydrates for low-temperature heat storage applications.
It can be used as an efficient carrier for multiparticulate sustained drug delivery. For example, it can be used to develop polymeric microspheres for the controlled release of Ivabradine HCL (IBH).
It can be used as an efficient carrier for multiparticulate sustained drug delivery. For example, it can be used to develop polymeric microspheres for the controlled release of Ivabradine HCL (IBH).
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Acta poloniae pharmaceutica, 69(1), 11-22 (2012-05-12)
Ethylcellulose (EC) based microencapsulated drug delivery systems are being extensively studied throughout the world for achieving extended drug release and protecting the core substance from degradation. The in vitro evaluation of EC microcapsules have elucidated that their particle characteristics are
International journal of pharmaceutics, 436(1-2), 88-96 (2012-07-14)
A drug-loaded nanofiber mesh which could achieve time-engineeringed biphasic release was fabricated through sequential electrospinning. The drug to polymer ratio of each single mesh was allocated and designed before the tri-layered meshes were created. The resultant meshes had the following
Expert opinion on drug delivery, 9(12), 1463-1474 (2012-10-16)
To examine the potential of a novel 3-fluid nozzle spray drying technology to formulate differentiated layered microparticles (MPs) of diclofenac sodium (DFS)/ethyl cellulose (EC). DFS/EC MPs were formulated using the inner and/or outer nozzles of a novel 3-fluid nozzle and
Applied biochemistry and biotechnology, 169(3), 1026-1038 (2013-01-09)
The chemical modification of developed ethyl cellulose-based membrane was carried out to make it suitable for bioseparation. The different reagents were used for the modification of membrane to couple protein A (PA) to study the purification of immunoglobulin G (IgG)
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