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93690

Sigma-Aldrich

L-Tryptophan ethyl ester hydrochloride

≥99.0% (AT)

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About This Item

Empirical Formula (Hill Notation):
C13H16N2O2 · HCl
CAS Number:
2899-28-7
Molecular Weight:
268.74
Beilstein:
3919010
EC Number:
220-786-0
MDL number:
MFCD00038993
UNSPSC Code:
12352209
PubChem Substance ID:
57653572
NACRES:
NA.22

Assay

≥99.0% (AT)

form

powder

optical activity

[α]20/D +10±1°, c = 2% in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

220-225 °C (dec.)

application(s)

peptide synthesis

SMILES string

Cl.CCOC(=O)[C@@H](N)Cc1c[nH]c2ccccc12

InChI

1S/C13H16N2O2.ClH/c1-2-17-13(16)11(14)7-9-8-15-12-6-4-3-5-10(9)12;/h3-6,8,11,15H,2,7,14H2,1H3;1H/t11-;/m0./s1

InChI key

PESYCVVSLYSXAK-MERQFXBCSA-N

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Related Categories

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Kento Takayama et al.
Journal of natural medicines, 75(1), 116-128 (2020-10-21)
Indole is produced from dietary tryptophan by tryptophanase in intestinal bacteria, such as Escherichia coli. In the liver, indole is converted into indoxyl sulfate, a uremic toxin and risk factor for chronic kidney disease (CKD). Probiotics and prebiotics are currently
V Iu Shviadas et al.
Biokhimiia (Moscow, Russia), 45(4), 629-635 (1980-04-01)
The hydrolysis of L-tryptophane ethyl ester catalyzed by alpha-chymotrypsin and the effect of ethyl ster of D-tryptophane on the course of the reaction were studied. A kinetic pattern of a three-step enzymatic reaction based on the assumption that the enzyme
Ashok Jadhav et al.
British journal of pharmacology, 166(1), 232-242 (2011-09-29)
L-tryptophan (L-W) is a precursor of the vasoconstrictor, 5-HT. However, acute administration of L-W ethyl ester (L-Wee) lowered blood pressure. The mechanism of action is unknown. This study compares the vascular effects of L-W and L-Wee in intact animals, isolated
F L Tse et al.
The Journal of pharmacy and pharmacology, 36(9), 633-636 (1984-09-01)
Sandoz compound 57-118 is a mixture of tryptophan ethyl ester amide derivatives (analogues I-V) possessing one of five fatty acid chains which differ in chain length, configuration, or the degree of unsaturation. The relative absorption of each of the five
Jian Xiang Zhang et al.
Journal of controlled release : official journal of the Controlled Release Society, 116(3), 322-329 (2006-11-18)
The effects of copolymer composition, drug structure and initial drug feed on drug loading of polymeric micelles based on amphiphilic polyphosphazenes were investigated. It was found that the drug loading capacity of micelles based on this type of amphiphilic copolymers
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