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E45309

Sigma-Aldrich

Ethyl phenylpropiolate

98%

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About This Item

Linear Formula:
C6H5C≡CCOOC2H5
CAS Number:
2216-94-6
Molecular Weight:
174.20
Beilstein:
639637
EC Number:
218-703-8
MDL number:
MFCD00009185
UNSPSC Code:
12352100
PubChem Substance ID:
24894561
NACRES:
NA.22

Assay

98%

form

liquid

refractive index

n20/D 1.552 (lit.)

bp

260-270 °C (lit.)

density

1.055 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CCOC(=O)C#Cc1ccccc1

InChI

1S/C11H10O2/c1-2-13-11(12)9-8-10-6-4-3-5-7-10/h3-7H,2H2,1H3

InChI key

ACJOYTKWHPEIHW-UHFFFAOYSA-N

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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G S Cameron et al.
Cancer research, 51(20), 5642-5648 (1991-10-15)
The ability of the hyperplasiogenic irritant ethyl phenylpropiolate (EPP) to act as a tumor promoter in two-stage carcinogenesis and to stimulate cellular events commonly cited as markers of tumor promoter action was evaluated. Treatment of adult, inbred SENCAR (SSIN) mice
Ampai Panthong et al.
Journal of ethnopharmacology, 91(2-3), 237-242 (2004-05-04)
Methanolic extracts from the heart wood, stem bark, and stem wood of Ventilago harmandiana Pierre (Family Rhamnaceae) were assessed for anti-inflammatory effects using both acute and chronic inflammatory models. Analgesic and antipyretic activities of the extracts were also evaluated. It
K A Davidson et al.
The Journal of investigative dermatology, 79(6), 378-382 (1982-12-01)
Glucocorticoids (anti-inflammatory steroids) are very potent inhibitors of mouse skin tumor promotion induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). This report describes a high-affinity, limited-capacity binding component which specifically interacts with glucocorticoids and which is identified as a glucocorticoid (GC) receptor present in
J E Paulsen
Carcinogenesis, 11(8), 1255-1258 (1990-08-01)
We examined the effects of retinoic acid (RA) on epidermal DNA synthesis, induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), a strong tumor promoter; mezerein (MEZ), a strong second stage promoter or ethylphenylpropiolate (EPP), a weak tumor promoter. RA reduced the initial wave of
M Takigawa et al.
Cancer research, 46(1), 106-112 (1986-01-01)
More than one application of the potent tumor-promoting agent, 12-O-tetradecanoylphorbol-13-acetate (TPA), to mouse skin at intervals of more than 48 h led to a larger induction of ornithine decarboxylase (EC 4.1.1.17; ODC) than did a single application. In contrast, at
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