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Key Documents

324558

Sigma-Aldrich

Ethylene glycol

anhydrous, 99.8%

Synonym(s):

1,2-Ethanediol

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About This Item

Linear Formula:
HOCH2CH2OH
CAS Number:
Molecular Weight:
62.07
Beilstein:
505945
EC Number:
MDL number:
UNSPSC Code:
12191502
eCl@ss:
39020501
PubChem Substance ID:
NACRES:
NA.21

grade

anhydrous

Quality Level

vapor density

2.1 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)

Assay

99.8%

form

liquid

autoignition temp.

752 °F

expl. lim.

15.3 %

impurities

<0.003% water
<0.005% water (100 mL pkg)

refractive index

n20/D 1.431 (lit.)

bp

195-198 °C

mp

−13 °C (lit.)

density

1.113 g/mL at 25 °C (lit.)

SMILES string

OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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General description

Ethylene glycol is the major component of antifreeze preparations.

Application

Ethylene glycol may be used in the preparation of spiroborate esters by reacting with chiral 1,2-aminoalcohols in the presence of triisopropyl borate. It may also be used as a solvent in the preparation of tris(2,2′-bipyrazyl)ruthenium(II) chloride by the reaction of 2,2′-bipyrazine with ruthenium(III) chloride.

Pictograms

Health hazardExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - STOT RE 2 Oral

Target Organs

Kidney

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

239.0 °F - open cup

Flash Point(C)

115 °C - open cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Synthesis of spiroborate esters from 1,2-aminoalcohols, ethylene glycol and triisopropyl borate: preparation of (S)-1-(1,3,2-dioxaborolan-2-yloxy)-3-methyl-1,1-diphenylbutan-2-amine
Stepanenko V, et al.
Organic Syntheses, 87, 26-26 (2010)
The spectrum of ethylene glycol poisoning.
Moriarty RW & McDonald RH.
Clinical Toxicology, 7(6), 583-596 (1974)
Bis(tetrakis(3,5-bis(trifluoromethyl)phenyl)borate)
Lies SD, et al.
Organic Syntheses, 93, 178-178 (2016)
Birgit Oberleitner et al.
Chemical communications (Cambridge, England), 49(16), 1615-1617 (2013-01-23)
This work describes an integrated approach for designing on demand Self-Assembled Monolayers (SAMs) on silicon oxides and particularly glass substrates for cell biology applications. Starting from commercially available compounds, the strategy relies on thiol-ene reaction and provides high quality SAMs
Mona Sheikhi et al.
Fertility and sterility, 100(1), 170-177 (2013-04-10)
To study the preservation of follicles within ovarian tissue vitrified using only one or a combination of three permeating cryoprotectants. Experimental study. University hospital. Ovarian tissue was donated by consenting women undergoing elective cesarean section. Ovarian tissue was vitrified in

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