D6001

Dextran sulfate sodium salt from Leuconostoc spp.

average mol wt >500,000 (dextran starting material), contains 0.5-2.0% phosphate buffer, pH 6-8

• CAS Number: 9011-18-1
• MDL number: MFCD00081551
• UNSPSC Code: 12352201
• NACRES: NA.21

Properties

• biological source: bacterial (Leuconostoc mesenteroides)
• Quality Level: 200
• form: powder
• optical activity: [α]/D 90 to 105 °, c = 6% (w/v) in water
• mol wt: average mol wt >500,000 (dextran starting material)
• contains: 0.5-2.0% phosphate buffer, pH 6-8
• composition: Sulfur Content, 16.0-19.0%
• color: white to off-white
• useful pH range: 6.0-8.0 (1% in water)
• solubility: H₂O: 100 mg/mL

Description

General description

Dextran sulfate is a negatively charged sulfated polysaccharide, which is produced by the esterification of dextran with chlorosulphonic acid. It has antiviral, anticoagulant and adjuvant properties. Dextran is used to treat hemorrhage, burns, surgery and trauma. It enhances blood flow and blocks erythrocyte aggregation. Dextran decreases the risk of thrombosis and postoperative pulmonary emboli. It acts as a ribonuclease inhibitor.

Application

Dextran sulfate sodium salt Leuconostoc spp has been used:

• to delipidate fatty plasma(67)(70)
• to induce inflammatory and carcinogenic response in the distal colon of rodents(68)
• for the preparation of 3,4-ethylenedioxythiophene (EDOT)(69)

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves