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Key Documents

N2515

Supelco

D-Norpropoxyphene maleate salt

analytical standard

Synonym(s):

1,2-Diphenyl-3-methyl-4-(methylamino)-2-butyl propionate

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About This Item

Empirical Formula (Hill Notation):
C21H27NO2 · C4H4O4
CAS Number:
Molecular Weight:
441.52
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

OC(=O)\C=C/C(O)=O.CCC(=O)OC(Cc1ccccc1)(C(C)CNC)c2ccccc2

InChI

1S/C21H27NO2.C4H4O4/c1-4-20(23)24-21(17(2)16-22-3,19-13-9-6-10-14-19)15-18-11-7-5-8-12-18;5-3(6)1-2-4(7)8/h5-14,17,22H,4,15-16H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

HCQPFYNZJNOOKN-BTJKTKAUSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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M Franke et al.
Forensic science international, 81(1), 51-59 (1996-07-31)
Microwave irradiation is used as an alternative heating method for extraction over more conventional hot plate methods. We describe a fast, efficient method for the determination of selected drugs in human blood/serum using microwave extraction. The microwave extraction of organic
Bridgit Crews et al.
Journal of analytical toxicology, 33(7), 379-383 (2009-10-03)
A "dilute and shoot" method for measuring norpropoxyphene in human urine using liquid chromatography-tandem mass spectrometry distinguishes two different metabolites of propoxyphene, norpropoxyphene (m/z 326) and a dehydrated rearrangement product (m/z 308). The metabolite formed from the rearrangement and dehydration
Simultaneous determination of propoxyphene and norpropoxyphene in biological samples by gas chromatography using an on-column injection technique with a fused-silica capillary column.
H Shin et al.
Journal of chromatography, 491(2), 448-454 (1989-07-21)
Henry J Carson et al.
Journal of forensic and legal medicine, 15(6), 395-397 (2008-07-01)
We encountered a decedent with an unexpected glioblastoma multiforme. A 61-year-old retired African-American woman was found dead in her home, fully clothed in her bathtub, with a pillow under her head. At autopsy, the brain showed a glioblastoma multiforme. Toxicology
R J Flanagan et al.
British journal of clinical pharmacology, 28(4), 463-469 (1989-10-01)
1. The pharmacokinetics of dextropropoxyphene (D) and nordextropropoxyphene (ND) have been studied in 12 healthy young (21-28 years) and 12 healthy elderly (70-79 years) male and female subjects. Each received 65 mg D and plasma D and ND concentrations were

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