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Key Documents

Y0001581

Alimemazine for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Alimemazine hemitartrate

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About This Item

Empirical Formula (Hill Notation):
C18H22N2S · 0.5C4H6O6
CAS Number:
4330-99-8
Molecular Weight:
373.49
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

alimemazine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/2C18H22N2S.C4H6O6/c2*1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)21-18-11-7-5-9-16(18)20;5-1(3(7)8)2(6)4(9)10/h2*4-11,14H,12-13H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..1/s1

InChI key

AJZJIYUOOJLBAU-CEAXSRTFSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Alimemazine for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Precautionary Statements

P301 + P330 + P331 + P310

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

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N Richman
Journal of child psychology and psychiatry, and allied disciplines, 26(4), 591-598 (1985-07-01)
A double-blind trial using trimeprazine tartrate was carried out in 22 children with severe waking problems. On parental verbal reports sleep was significantly improved on the drug compared with the original baseline and the placebo, but diaries kept by the
K A Payne et al.
Acta anaesthesiologica Belgica, 43(3), 173-179 (1992-01-01)
One hundred and twenty-three male children, aged one to ten years, were studied to determine the influence of premedication on changes in patterns of behaviour following hospitalization for repair of inguinal hernias. Four comparable groups were selected for premedication regimen:
ABC of 1 to 7. Sleep problems.
H B Valman
British medical journal (Clinical research ed.), 283(6288), 422-423 (1981-08-08)
Potentiation of radiation response of a mouse fibrosarcoma by phenothiazine drugs.
K C George et al.
Indian journal of experimental biology, 22(6), 305-307 (1984-06-01)
K G France et al.
Experimental and clinical psychopharmacology, 7(4), 502-513 (1999-12-28)
Infant sleep disturbance involving chronic night waking and resistance to settling to sleep or returning to sleep is a common problem for families with children 6-27 months old. Prescription and nonprescription sedatives are frequently administered without clear evidence that they
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