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45690

Sigma-Aldrich

Erythrosin extra bluish

for microscopy (Bact., Hist.), adsorption and fluorescent indicator

Synonym(s):

2′,4′,5′,7′-Tetraiodofluorescein disodium salt, Acid Red 51, Iodoeosin

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About This Item

Empirical Formula (Hill Notation):
C20H6I4Na2O5
CAS Number:
16423-68-0
Molecular Weight:
879.86
Colour Index Number:
45430
Beilstein:
1443945
EC Number:
240-474-8
MDL number:
MFCD00144257
UNSPSC Code:
12171500
PubChem Substance ID:
329756903
NACRES:
NA.47

grade

adsorption and fluorescent indicator
for microscopy (Bact., Hist.)

Quality Level

100

form

solid

technique(s)

titration: suitable

SMILES string

[Na+].[Na+].[O-]c1c(I)cc2c(Oc3c(I)c([O-])c(I)cc3C24OC(=O)c5ccccc45)c1I

InChI

1S/C20H8I4O5.2Na/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20;;/h1-6,25-26H;;/q;2*+1/p-2

InChI key

RAGZEDHHTPQLAI-UHFFFAOYSA-L

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General description

Erythrosin extra bluish is a brown color powder, that is soluble in ethanol and water. Its pH ranges from 2.5 to 4. It is used in color filters, light emitting diodes, cosmetics, hair dyes etc. It has several biological applications like detecting gene expression, treating age related macular degeneration, diabetes, obesity etc.

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H302 - H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

359.6 °F - closed cup

Flash Point(C)

182 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Wei Zhang et al.
Journal of the American Chemical Society, 133(51), 20680-20683 (2011-12-03)
We report the use of a simple complex assembled from Ni(II) salt and 2-mecaptoethanol in one step in water as the efficient catalyst in a molecular hydrogen system which can be sensitized by a low-cost xanthene dye, Erythrosin B. An
Farah Maria Drumond Chequer et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(10), 3447-3451 (2012-08-01)
Erythrosine (ErB) is a xanthene and an US Food and Drug Administration approved dye used in foods, drugs and cosmetics. Although its utilization is permitted, ErB is described as inhibitor of enzymes and protein-protein interactions and is toxic to pituitary
Young-Ho Lee et al.
International journal of oral science, 4(4), 196-201 (2012-12-12)
The purpose of our study was to evaluate the effect of photodynamic therapy (PDT), using erythrosine as a photosensitizing agent and a dental halogen curing unit as a light source, on Streptococcus mutans in a biofilm phase. The S. mutans
Anna Carolina Borges Pereira Costa et al.
Archives of oral biology, 56(11), 1299-1305 (2011-06-28)
The effect of erythrosine- and LED-mediated photodynamic therapy (PDT) on planktonic cultures and biofilms of Candida albicans and Candida dubliniensis was evaluated. Planktonic cultures of standardized suspensions (10(6)cells/mL) of C. albicans and C. dubliniensis were treated with erythrosine concentrations of
Juliana P M L Rolim et al.
Journal of photochemistry and photobiology. B, Biology, 106, 40-46 (2011-11-11)
Several photosensitizers have been used against oral bacteria without standardization. Singlet oxygen ((1)O(2)) is an aggressive chemical species that can kill cells through apoptosis or necrosis. to compare the antimicrobial activity of photodynamic therapy (PDT) with different photosensitizers at the
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