G7253
Ginseng root from Panax quinquefolium (American ginseng)
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About This Item
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biological source
Panax quinquefolium
form
powder
General description
Ginseng comprises of saponins called ginsenosides, acidic polysaccharides and polyphenolic compounds.
Ginseng is an important herbal remedy extensively used to improve cardiac health and circulation. Treatment with Panax ginseng has shown to improve cardiac performance. It also increases protection against myocardial ischemia/reperfusion damage by enhancing nitric oxide (NO) release.
Application
American ginseng (Panax quinquefolium) was used to test its protective effects against mitomycin C induced micronuclei in mice. It is used to test the adaptogenic and anti-amnesic properties of evolvulus alsinoides in rodents.
Ginseng root from Panax quinquefolium (American ginseng) has been used as control in hyperlocomotor activity studies and adaptogenic activity screening in mice.
Biochem/physiol Actions
Ginseng is an effective immune modulator and improves phagocytic functionality of macrophages and stimulates natural killer cells. Ginseng elicits anticancer and anti-diabetic functionality. Ginseng may provide protection in neurodegenerative diseases like Parkinson′s disease and Alzheimer′s disease. Ginseng improves liver regeneration and is effective in treating hepatocellular carcinoma.
Quality
Crude powder
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Phytotherapy research : PTR, 21(12), 1221-1227 (2007-07-31)
Mitomycin C (MMC) is a highly active anticancer drug commonly used alone and in combination with other chemotherapeutic agents for the treatment of different cancers. Its bioactivated form critically damages the DNA present in both rapidly dividing cancerous cells as
Pharmacological effects of ginseng on liver functions and diseases: a minireview
Evidence-Based Complementary and Alternative Medicine : ECAM, 2012 (2012)
Evaluation of the antipsychotic potential of Panax quinquefolium in ketamine induced experimental psychosis model in mice
Neurochemical Research, 37(4), 759-770 (2012)
Pharmacology, biochemistry, and behavior, 81(3), 424-432 (2005-05-19)
Evolvulus alsinoides (EA) is well known for its memory enhancement, antiepileptic and immunomodulatory properties in the traditional Indian system of medicine, Ayurveda. In view of the increasing attention towards plants offering non-specific resistance (adaptogens) towards stress, we have evaluated crude
Ginseng, the'immunity boost': the effects of Panax ginseng on immune system
Journal of ginseng research, 36(4), 354-354 (2012)
Articles
Optimize HPLC method for ginsenoside separation using a mixture, applying it to American Ginseng root, with conditions and chromatograms shown.
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