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G7387

Sigma-Aldrich

Gly-His-Lys acetate salt

BioXtra, γ-irradiated, suitable for cell culture

Synonym(s):

Liver cell growth factor

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About This Item

Linear Formula:
C14H24N6O4C2H4O2
CAS Number:
72957-37-0
Molecular Weight:
400.43
MDL number:
MFCD00012699
UNSPSC Code:
12352209
PubChem Substance ID:
24895305
NACRES:
NA.77

biological source

synthetic (organic)

Quality Level

200

sterility

γ-irradiated

product line

BioXtra

form

powder

mol wt

400.43 g/mol

packaging

pkg of 5 mg

technique(s)

cell culture | mammalian: suitable

impurities

<2 EU/mL

color

white

solubility

H2O: soluble 0.5 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

CC(O)=O.NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CN)C(O)=O

InChI

1S/C14H24N6O4.C2H4O2/c15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9;1-2(3)4/h7-8,10-11H,1-6,15-16H2,(H,17,18)(H,19,21)(H,20,22)(H,23,24);1H3,(H,3,4)/t10-,11-;/m0./s1

InChI key

MGNUTAFMLGJBGV-ACMTZBLWSA-N

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Amino Acid Sequence

Gly-His-Lys

Application

Gly-His-Lys acetate salt has been used:
  • as a component of the serum-containing medium to culture human thyroid cells
  • as a supplement to culture fisher rat thyroid cells
  • as a component of the Dulbecco′s modified Eagle Medium (DMEM)/HamF12/mesenchymal stem cell media to culture mesenchymal stem cells

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Lars Kayser et al.
Acta histochemica, 107(1), 31-41 (2005-05-04)
The objective was to investigate glucose-6-phosphate dehydrogenase (G6PD) activity in monolayer cultures of thyroid epithelial cells and to examine whether inhibition of nitric oxide synthase affects activity of G6PD or oxygen sensitivity of the assay. Primary cultures without TSH addition
Hosny Salama et al.
Stem cell research & therapy, 5(3), 70-70 (2014-06-03)
We have assessed the utility of autologous mesenchymal stem cell (MSC) peripheral vein infusion as a possible therapeutic modality for patients with end-stage liver diseases. Forty patients with post-hepatitis C virus (HCV) end-stage liver disease were randomized into two groups:
Lars Kayser et al.
Acta histochemica, 107(1), 31-41 (2005-05-04)
The objective was to investigate glucose-6-phosphate dehydrogenase (G6PD) activity in monolayer cultures of thyroid epithelial cells and to examine whether inhibition of nitric oxide synthase affects activity of G6PD or oxygen sensitivity of the assay. Primary cultures without TSH addition
Christelle Hureau et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 17(36), 10151-10160 (2011-07-23)
The Gly-His-Lys (GHK) peptide and the Asp-Ala-His-Lys (DAHK) sequences are naturally occurring high-affinity copper(II) chelators found in the blood plasma and are hence of biological interest. A structural study of the copper complexes of these peptides was conducted in the
A Siméon et al.
The Journal of investigative dermatology, 115(6), 962-968 (2000-12-20)
Glycyl-histidyl-lysine-Cu(2+) is a tripeptide-copper complex previously shown to be an activator of wound healing. We have investigated the effects of glycyl-histidyl-lysine-Cu(2+) on the synthesis of glycosaminoglycans and small proteoglycans in a model of rat experimental wounds and in rat dermal
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