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M2015

Sigma-Aldrich

1-Stearoyl-rac-glycerol

≥99%

Synonym(s):

MG(18:0/0:0/0:0)[rac], 1-Monooctadecanoyl-rac-glycerol, rac-Glycerol 1-stearate, DL-α-Stearin, Monostearin

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About This Item

Linear Formula:
CH3(CH2)16COOCH2CH(OH)CH2OH
CAS Number:
123-94-4
Molecular Weight:
358.56
Beilstein:
1728685
EC Number:
204-664-4
MDL number:
MFCD00036186
UNSPSC Code:
51191904
PubChem Substance ID:
24896595
NACRES:
NA.25

biological source

synthetic (organic)

Quality Level

200

Assay

≥99%

form

powder

functional group

phospholipid

lipid type

neutral glycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO

InChI

1S/C21H42O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h20,22-23H,2-19H2,1H3

InChI key

VBICKXHEKHSIBG-UHFFFAOYSA-N

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Related Categories

Application

Monostearin (1-Stearoyl-rac-glycerol) is used in the development of drug delivery vehicles such as nanoparticles and microemulsions.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000420153
0000420140
0000420140
0000420153
0000404618

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Sagar S Bachhav et al.
International journal of pharmaceutics, 532(1), 612-622 (2017-09-25)
The oral uptake of intact nanocarriers through Peyer's patches is an important uptake pathway. We report Rifampicin Lipid-Polymer hybrid nanoparticles (RIF-LIPOMER) using glyceryl monostearate as lipid and the mucoadhesive polymer, Gantrez, with the objective of balancing hydrophobicity and mucoadhesion for
Howida Kamal Ibrahim et al.
Drug delivery, 23(9), 3181-3192 (2016-03-05)
Statins proved potential bone healing properties. Rosuvastatin is a synthetic, hydrophilic, potent and highly efficacious statin. In the current work, an attempt was investigated to develop, evaluate various bioerodible composite sponges enclosing rosuvastatin and explore their potential in augmenting bone
Maria Christina Camasmie Peters et al.
Journal of drug targeting, 28(3), 259-270 (2019-09-07)
Nanocrystals and lipid-based nanosystems have the potential to play a crucial role in a significant shift in the treatment of ophthalmic diseases. These drug delivery systems allow overcoming the barriers imposed by anatomy and physiology of the organ of vision.
Laizhu Zhang et al.
Drug delivery, 23(9), 3529-3537 (2016-06-25)
Transdermal local anesthesia is one of the most applied strategies to avoid systemic adverse effects; there is an appealing need for a prolonged local anesthetic that would provide better bioavailability and longer pain relief with a single administration. Layer-by-layer (LBL)
Min Fang et al.
International journal of nanomedicine, 7, 5395-5404 (2012-10-24)
Curcumin has a variety of pharmacological effects. However, poor water solubility and low oral bioavailability limit its clinical utility. A delivery system for nanostructured lipid carriers has been reported to be a promising approach to enhancing the oral absorption of
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