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N3002

Sigma-Aldrich

Bis(p-nitrophenyl) phosphate sodium salt

chromogenic, ≥99% (TLC), powder

Synonym(s):

BNPP sodium salt, Sodium bis(4-nitrophenyl) phosphate

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About This Item

Linear Formula:
C12H8O8N2PNa
CAS Number:
Molecular Weight:
362.16
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32

product name

Bis(p-nitrophenyl) phosphate sodium salt, ≥99% (TLC)

Quality Level

Assay

≥99% (TLC)

form

powder

impurities

≤0.05% free p-nitrophenol

solubility

water: 20 mg/mL, clear to very slightly hazy

storage temp.

−20°C

SMILES string

[Na].OP(=O)(Oc1ccc(cc1)N(=O)=O)Oc2ccc(cc2)N(=O)=O

InChI

1S/C12H9N2O8P.Na.H/c15-13(16)9-1-5-11(6-2-9)21-23(19,20)22-12-7-3-10(4-8-12)14(17)18;;/h1-8H,(H,19,20);;

InChI key

NXXNKMXTNUUECE-UHFFFAOYSA-N

Related Categories

Application

Bis(p-nitrophenyl) phosphate sodium salt has been used as a substrate for the estimation of phosphodiesterase (PDE) activity. It has also been used as a substrate in PDE inhibition assay.

Substrates

Phosphodiesterase substrate

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Elution of tightly bound solutes from concanavalin A Sepharose: Factors affecting the desorption of cottonmouth venom glycoproteins
Soper AS and Aird SD
Journal of Chromatography A, 1154(1-2), 308-318 (2007)
6-Nitrobenzimidazole derivatives: Potential phosphodiesterase inhibitors: Synthesis and structure-activity relationship
Khan KM, et al.
Bioorganic & Medicinal Chemistry, 20(4), 1521-1526 (2012)
Nucleotidase and DNase activities in Brazilian snake venoms
Sales PB, et al.
Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP, 147(1), 85-95 (2008)
M-C Chang et al.
Acta biomaterialia, 8(3), 1380-1387 (2011-09-29)
Biocompatibility of dentin bonding agents (DBA) and composite resin may affect the treatment outcome (e.g., healthy pulp, pulpal inflammation, pulp necrosis) after operative restoration. Bisphenol-glycidyl methacrylate (BisGMA) is one of the major monomers present in DBA and resin. Prior studies
Nele Steens et al.
Dalton transactions (Cambridge, England : 2003), (2)(2), 585-592 (2009-12-22)
Hydrolysis of 4-nitrophenyl phosphate (NPP) and bis-4-nitrophenyl phosphate (BNPP), two commonly used DNA model substrates, was examined in vanadate solutions by means of (1)H, (31)P and (51)V NMR spectroscopy. The hydrolysis of the phosphoester bond in NPP at 50 degrees

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