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Oleanane-type isomeric triterpenoids from Barringtonia racemosa.

Journal of natural products (2009-04-25)
P Mangala Gowri, S V S Radhakrishnan, S Jeelani Basha, A V S Sarma, J Madhusudana Rao
ABSTRACT

Two new isomeric acylated oleanane-type triterpenoids along with three known compounds were isolated from the MeOH extract of the dried fruits of Barringtonia racemosa. On the basis of spectroscopic methods, with special emphasis on 1D and 2D NMR techniques as well as chemical methods, the structures were characterized as racemosol A (1) [22alpha-acetoxy-3beta,15alpha,16alpha,21beta-tetrahydroxy-28-(2-methylbutyryl)olean-12-ene] and isoracemosol A (2) [21beta-acetoxy-3beta,15alpha,16alpha,28-tetrahydroxy-22alpha-(2-methylbutyryl)olean-12-ene]. The isolated compounds (1-5) were not active against HeLa and P388 D1 carcinoma cell lines.

MATERIALS
Product Number
Brand
Product Description

Supelco
Stigmasterol, certified reference material, 10 mg/mL in chloroform
Sigma-Aldrich
Stigmasterol, ~95%