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930024

Sigma-Aldrich

Hyaluronic acid adipic dihydrazide (HA-ADH)

Synonym(s):

HA-ADH

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About This Item

Linear Formula:
(C20H33N5O12)n
UNSPSC Code:
12352125
NACRES:
NA.23

form

solid (Chunks)

Quality Level

100

color

white to off-white

application(s)

3D bioprinting

storage temp.

2-8°C

Related Categories

General description

Adipic acid dihydrazide is commonly used as a functional group to allow for HA cross-linking to polymers containing aldehyde groups or that are aldehyde-functionalized, like HA-aldehyde or PEG-aldehyde. These biomaterials are attractive for their tunable properties and low cytotoxicity.
Degree of functionalization (50-80%)

Application

Hyaluronic acid (HA) is a ubiquitous extracellular matrix component, which makes it attractive for use in medical applications for it′s biocompatibility and low immunogenicity. HA-based polymers are used to make hydrogels for a wide variety of applications from tissue engineering and regeneration to drug delivery and bioinks for 3D bioprinting. To make hydrogels, HA has to be derivatized with groups that can cross-link to to other functionalized polymers.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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