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A8060

Sigma-Aldrich

Acrylic acid N-hydroxysuccinimide ester

≥90%, for peptide synthesis

Synonym(s):

N-Acryloxysuccinimide

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About This Item

Empirical Formula (Hill Notation):
C7H7NO4
CAS Number:
Molecular Weight:
169.13
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22

product name

Acrylic acid N-hydroxysuccinimide ester, ≥90%

Quality Level

Assay

≥90%

form

powder

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

C=CC(=O)ON1C(=O)CCC1=O

InChI

1S/C7H7NO4/c1-2-7(11)12-8-5(9)3-4-6(8)10/h2H,1,3-4H2

InChI key

YXMISKNUHHOXFT-UHFFFAOYSA-N

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Application

Acrylic acid N-hydroxysuccinimide ester (NAS) is a general acrylating agent that is used in the synthesis of:
  • Acrylated hyaluronic acid (HA) hydrogel for bone regeneration applications.
  • Injectable, biodegradable, and thermosensitive copolymers for tissue engineering.
  • Imidazole-based biocompatible, aqueous quantum dots (QDs).

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Protein-reactive, thermoresponsive copolymers with high flexibility and biodegradability.
Guan J, et al.
Biomacromolecules, 9(4), 1283-1292 (2008)
Avin Ramaiya et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(41), 10894-10899 (2017-10-05)
Cytoskeletal motors drive many essential cellular processes. For example, kinesin-1 transports cargo in a step-wise manner along microtubules. To resolve rotations during stepping, we used optical tweezers combined with an optical microprotractor and torsion balance using highly birefringent microspheres to
Bone regeneration using hyaluronic acid-based hydrogel with bone morphogenic protein-2 and human mesenchymal stem cells.
Kim J, et al.
Biomaterials, 28(10), 1830-1837 (2007)
Fred Y Shen et al.
Nature communications, 11(1), 4632-4632 (2020-09-17)
Mapping neuroanatomy is a foundational goal towards understanding brain function. Electron microscopy (EM) has been the gold standard for connectivity analysis because nanoscale resolution is necessary to unambiguously resolve synapses. However, molecular information that specifies cell types is often lost
Raja Zaidatul Akhmar Raja Jamaluddin et al.
Sensors (Basel, Switzerland), 18(5) (2018-04-28)
A new biosensor for the analysis of nitrite in food was developed based on hemoglobin (Hb) covalently immobilized on the succinimide functionalized poly(n-butyl acrylate)-graphene [poly(nBA)-rGO] composite film deposited on a carbon-paste screen-printed electrode (SPE). The immobilized Hb on the poly(nBA)-rGO

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