M0505
Methylamine hydrochloride
≥98%
Synonym(s):
Methanaminium chloride, Methylamine monohydrochloride, Methylammonium chloride, Monomethylammonium chloride
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About This Item
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Quality Level
Assay
≥98%
form
powder or crystals
bp
225-230 °C/15 mmHg (lit.)
mp
231-233 °C (lit.)
solubility
H2O: 1 g in 10 mL, clear, colorless
SMILES string
Cl[H].CN
InChI
1S/CH5N.ClH/c1-2;/h2H2,1H3;1H
InChI key
NQMRYBIKMRVZLB-UHFFFAOYSA-N
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General description
Methylamine hydrochloride is used as a buildingblock for the synthesis of various organic compounds.
Application
Methylamine hydrochloride can be used as a reactant to synthesize:
- Betahistine via aza-Michael reaction with 2-vinylpyridine in water.
- Azatripyrrolic and azatetrapyrrolic macrocycles by reacting with pyrrole and formaldehyde via base-catalyzed Mannich reaction.
- Tetrahydropyridines via Aza-Diels–Alder reaction with dienes and aldehydes.
- N-methylsecondary arylamines from aryl chlorides via nickel-catalyzed amination reaction.
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
408.7 °F - closed cup
Flash Point(C)
209.3 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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