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W210901

Sigma-Aldrich

L-Ascorbic acid

FCC, FG

Synonym(s):

L-AA, L-Threoascorbic acid, Antiscorbutic factor, Vitamin C

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About This Item

Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
Molecular Weight:
176.12
FEMA Number:
2109
Beilstein:
84272
EC Number:
MDL number:
UNSPSC Code:
12164502
PubChem Substance ID:
NACRES:
NA.21

biological source

synthetic

Quality Level

grade

FG
Fragrance grade

Agency

follows IFRA guidelines

reg. compliance

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FCC
FDA 21 CFR 117
FDA 21 CFR 182.3013
FDA 21 CFR 182.8013

Assay

99.0-100.5% (iodometric)

form

crystalline
powder or crystals

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

color

white

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

water: soluble 176 g/L at 20 °C

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

no known allergens

Organoleptic

green

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

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General description

L-Ascorbic acid, an organic acid, is found abundantly in citrus fruits. It is generally used as an antioxidant and pH adjuster in the cosmetic industry. L-AA is also used as a preservative and nutrient supplement in foods.

Application


  • Integrated metabolomics of big six Escherichia coli on pea sprouts to organic acid treatments.: Explores the antimicrobial effects of organic acids including L-Ascorbic acid on E. coli strains, offering insights into its use in food safety practices (Wang Y et al., 2022).

  • Molecular Scalpel to Chemically Cleave Metal-Organic Frameworks for Induced Phase Transition.: Although not directly related to typical biochemical applications of L-Ascorbic acid, this innovative research uses it in material science to influence molecular structures, which could inform nanotechnology applications in biochemistry (Zhou X et al., 2021).

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Differential transcriptional regulation of L-ascorbic acid content in peel and pulp of citrus fruits during development and maturation
Alos E, et al.
Planta, 239(5), 1113-1128 (2014)
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics.
Elmore AR.
International Journal of Toxicology, 24, 51-111 (2005)
Dictionary of Food Compounds with CD-ROM: Additives, Flavors, and Ingredients, 113-113 (2012)
Determination of l-ascorbic acid in wines by direct injection liquid chromatography using a polymeric column
Lopes P, et al.
Analytica Chimica Acta, 555(2), 242-245 (2006)
Determination of l-ascorbic acid in human serum by chemiluminescence based on hydrogen peroxide--sodium hydrogen carbonate--CdSe/CdS quantum dots system
Chen H, et al.
Talanta, 81(4-5), 1688-1696 (2010)

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