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2-Methoxyethanol

analytical standard

Synonym(s):

Ethylene glycol monomethyl ether, Methyl glycol

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About This Item

Linear Formula:
CH3OCH2CH2OH
CAS Number:
Molecular Weight:
76.09
Beilstein:
1731074
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

vapor density

2.62 (vs air)

vapor pressure

6.17 mmHg ( 20 °C)

Assay

≥99.9% (GC)

autoignition temp.

548 °F

shelf life

limited shelf life, expiry date on the label

contains

~0.0005% 2,6-di-tert-butyl-4-methylphenol as stabilizer

expl. lim.

24.5 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.402 (lit.)
n20/D 1.402

bp

124-125 °C (lit.)

mp

−85 °C (lit.)

density

0.965 g/mL at 25 °C (lit.)

application(s)

environmental

format

neat

SMILES string

COCCO

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI key

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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General description

2-Methoxyethanol is an organic compound, which is commonly used as a solvent for industrial and consumer products.

Application

2-Methoxyethanol may be used as an analytical standard for the quantification of didanosine in biological samples using high performance liquid chromatography technique (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3 - Repr. 1B - STOT RE 2 - STOT SE 1

Target Organs

Immune system, thymus

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

104.0 °F - closed cup

Flash Point(C)

40 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Analysis of residual solvents by fast gas chromatography.
Chen KT, et al.
Journal of Chromatography A, 811(1-2), 145-150 (1998)
Quantitation of didanosine in human plasma and urine by high-performance liquid chromatography.
Knupp AC, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 533(1-2), 282-290 (1990)
Anna Maria Piras et al.
International journal of pharmaceutics, 357(1-2), 260-271 (2008-03-04)
The preparation of novel biocompatible polymeric nanoconstructs suitable to load sensitive bioactive protein agents is reported. Nanoparticles were prepared as based on hybrid polymeric matrices consisting of synthetic bioerodible alternating copolymers of maleic anhydride and n-butylvinylether hemiesterified with 2-methoxyethanol and
Makoto Takei et al.
Toxicological sciences : an official journal of the Society of Toxicology, 118(2), 643-652 (2010-07-10)
Ethylene glycol monomethyl ether (EGME) is a widely used industrial solvent known to cause adverse effects to human and other mammals. Organs with high metabolism and rapid cell division, such as testes, are especially sensitive to its actions. In order
Alberto Dessy et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 43(1-2), 57-64 (2011-03-30)
In the present work polymeric nanoparticles based on Poly (maleic anhydride-alt-butyl vinyl ether) 5% grafted with m-PEG (2000) and 95% grafted with 2-methoxyethanol (VAM41-PEG) were loaded with human hemoglobin (Hb) and characterized from a physicochemical point of view. The assessment

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