H4014

25-Hydroxycholecalciferol

≥98% (HPLC)

• Synonym(s): 25-Hydroxyvitamin D₃
• Empirical Formula (Hill Notation): C₂₇H₄₄O₂
• CAS Number: 19356-17-3
• Molecular Weight: 400.64
• EC Number: 242-990-9
• MDL number: MFCD00867077
• UNSPSC Code: 12352205
• PubChem Substance ID: 24895612
• NACRES: NA.79

Properties

• Quality Level: 200
• Assay: ≥98% (HPLC)
• form: powder
• technique(s): HPLC: suitable
• color: white to off-white
• storage temp.: −20°C
• SMILES string: C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C
• InChI: 1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
• InChI key: JWUBBDSIWDLEOM-DTOXIADCSA-N
• Gene Information: human ... VDR(7421)

Description

Application

• Immunoassay development 25-Hydroxycholecalciferol: An investigation into the safety and efficacy of 25-hydroxycholecalciferol produced with Saccharomyces cerevisiae for animal feed emphasized its potential application in developing immunoassays that monitor vitamin D levels in animals, providing a basis for similar applications in human diagnostics (EFSA Panel on Additives and Products, 2023).

Biochem/physiol Actions

Ergocalciferol (vitamin D2) and 25-Hydroxycholecalciferol (vitamin D3) are the two form of vitamin D which are activated in vivo by hydroxylation. Vitamin D2 and D3 may be used in a wide range of studies to assess their effects on function such as immune function and calcium homeostasis.

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H301 + H311,H330,H372
• Precautionary Statements: P260 - P264 - P280 - P302 + P352 + P312 - P304 + P340 + P310 - P314
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves