1269200

Famotidine

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Famotidine, N′-(Aminosulfonyl)-3-([2-(diaminomethyleneamino)-4-thiazolyl]methylthio)propanamidine
• Empirical Formula (Hill Notation): C₈H₁₅N₇O₂S₃
• CAS Number: 76824-35-6
• Molecular Weight: 337.45
• MDL number: MFCD00079297
• UNSPSC Code: 41116107
• PubChem Substance ID: 329749830
• NACRES: NA.24

Properties

• biological source: synthetic
• grade: pharmaceutical primary standard
• Agency: USP
• vapor pressure: <0.0000001 kPa ( 25 °C)
• API family: famotidine
• form: powder
• packaging: pkg of 125 mg
• manufacturer/tradename: USP
• storage condition: protect from light
• color: white to pale yellow-white
• mp: 325.4-327.2 °F (163—164°C)
• solubility: DMF: freely soluble; acetone: practically insoluble; chloroform: practically insoluble; ethanol: practically insoluble; ether: practically insoluble; ethyl acetate: practically insoluble; glacial acetic acid: freely soluble; methanol: slightly soluble; water: very slightly soluble
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: N\C(N)=N\c1nc(CSCCC(=N)NS(N)(=O)=O)cs1
• InChI: 1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)
• InChI key: XUFQPHANEAPEMJ-UHFFFAOYSA-N
• Gene Information: human ... HRH2(3274)

Description

General description

Famotidine is a hydrophilic, cationic, histamine H2 receptor antagonist drug that effectively inhibits gastric acid secretion in humans.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Famotidine can be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations by various analytical techniques.(10)

Biochem/physiol Actions

H₂ histamine receptor antagonist; anti-ulcer agent

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable