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219924

Sigma-Aldrich

4-Hydroxy-3-nitrophenylacetic acid

99%

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About This Item

Linear Formula:
HOC6H3(NO2)CH2CO2H
CAS Number:
10463-20-4
Molecular Weight:
197.14
EC Number:
233-948-0
MDL number:
MFCD00007122
UNSPSC Code:
12352100
PubChem Substance ID:
24853155
NACRES:
NA.22

Assay

99%

mp

146-148 °C (lit.)

solubility

ethanol: soluble 5%, clear, yellow to orange

SMILES string

OC(=O)Cc1ccc(O)c(c1)[N+]([O-])=O

InChI

1S/C8H7NO5/c10-7-2-1-5(4-8(11)12)3-6(7)9(13)14/h1-3,10H,4H2,(H,11,12)

InChI key

QBHBHOSRLDPIHG-UHFFFAOYSA-N

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General description

4-Hydroxy-3-nitrophenylacetic acid enhances the ice-nucleation activity of Xanthomonas campestris.

Application

4-Hydroxy-3-nitrophenylacetic acid was used in the synthesis of 4-hydroxy-3-nitrophenylacetyl caproic acid.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ryota Sato et al.
International immunology, 32(8), 499-507 (2020-02-16)
Aluminum precipitates have long been used as adjuvants for human vaccines, but there is a clear need for safer and more effective adjuvants. Here we report in a mouse model that the psoriasis drug Oxarol ointment is a highly effective
H Torigoe et al.
The Journal of biological chemistry, 270(38), 22218-22222 (1995-09-22)
To understand the mechanism of affinity maturation, we examined the antigen-antibody interactions between 4-hydroxy-3-nitrophenylacetyl (NP) caproic acid and the Fab fragments of three anti-NP antibodies, N1G9, 3B44, and 3B62, by isothermal titration calorimetry. The analyses have revealed that all of
P Bergqvist et al.
Mucosal immunology, 6(1), 122-135 (2012-07-13)
Whereas gut IgA responses to the microbiota may be multi-centered and diverse, little is known about IgA responses to T-cell-dependent antigens following oral immunizations. Using a novel approach, gut IgA responses to oral hapten (4-hydroxy-3-nitrophenyl)acetyl-cholera toxin (NP-CT) conjugates were followed
Masayuki Oda et al.
Molecular immunology, 47(2-3), 357-364 (2009-10-06)
The effect of antibody affinity on molecular forms of immune complexes was investigated by measuring antigen-antibody interactions using surface plasmon resonance (SPR), electrospray ionization time-of-flight mass spectrometry under non-denaturing conditions (MS), analytical ultracentrifugation (AUC), and transmission electron microscopy (TEM). (4-Hydroxy-3-nitrophenyl)acetic
Matthew D Taylor et al.
Frontiers in immunology, 11, 1946-1946 (2020-09-10)
Recent studies have demonstrated that induction of a diverse repertoire of memory T cells ("immune education") affects responses to murine cecal ligation and puncture (CLP), the most widely - used animal model of sepsis. Among the documented effects of immune
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