Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

A68300

Sigma-Aldrich

2-Aminopyridine-3-carboxylic acid

98%

Synonym(s):

2-Aminonicotinic acid, 2-Aminopyridine-3-carboxylic acid

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C6H6N2O2
CAS Number:
5345-47-1
Molecular Weight:
138.12
Beilstein:
119031
EC Number:
226-296-3
MDL number:
MFCD00006318
UNSPSC Code:
12352100
PubChem Substance ID:
24891144
NACRES:
NA.22

Assay

98%

form

powder

mp

295-297 °C (dec.) (lit.)

SMILES string

Nc1ncccc1C(O)=O

InChI

1S/C6H6N2O2/c7-5-4(6(9)10)2-1-3-8-5/h1-3H,(H2,7,8)(H,9,10)

InChI key

KPIVDNYJNOPGBE-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

2-Aminopyridine-3-carboxylic acid can be used as:
  • A ligand to prepare copper(II)-organic coordination compounds.
  • A reactant to prepare pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolines by reacting with trimethylsilyl cyanide and phthalaldehyde.
  • A reactant to synthesize organo-soluble and thermally stable poly(thiourea-amide-imide) polymers.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A J Dobson et al.
Acta crystallographica. Section C, Crystal structure communications, 53 ( Pt 10), 1427-1429 (1997-11-18)
2-Aminonicotinic acid, C6H6N2O2, crystallized in the centrosymmetric space group P2(1)/c in the zwitterionic form. Intermolecular N--H...O hydrogen bonds with N...O distances of 2.652 (2) and 2.807 (2) A link molecules into two sets of zigzag chains propagating along the b
Novel thermally stable poly (thiourea-amide-imide) s bearing CS moieties and pyridine units in the backbone: Synthesis and properties
Kausar A, et al.
Polymer Degradation and Stability, 95(12), 2611-2618 (2010)
Ronald Bartzatt
Drugs in R&D, 8(6), 363-372 (2007-10-30)
Nitrogen mustard (N-mustard) compounds are considered important anticancer drugs. Various transporting agents have been utilised to carry N-mustard groups including coumarins, amides, polyaromatic molecules and cycloalkyl structures. N-mustards act as bifunctional alkylating agents that induce cross-linking within DNA strands and
Synthesis, characterization, spectroscopic and electrochemical investigation of 2-aminopyridine-3-carboxylic acid copper (II) complexes with diimine
Srivastava AK, et al.
Chemical Data Collections, 24, 100272-100272 (2019)
Y Ohba et al.
Chemical & pharmaceutical bulletin, 48(8), 1236-1238 (2000-08-26)
To develop a sensitive and selective chemiluminometric method for the determination of methylglyoxal, we used 2-aminonicotinic acid as the chemiluminescence derivatization reagent. 2-Aminonicotinic acid reacts with methylglyoxal in an acidic solution at 37 degrees C for 4 h and gave
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service