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Key Documents

O3132

Sigma-Aldrich

Oxibendazole

~98%

Synonym(s):

Methyl (5-propoxy-1H-benzimidazol-2-yl)carbamate

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About This Item

Empirical Formula (Hill Notation):
C12H15N3O3
CAS Number:
Molecular Weight:
249.27
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

~98%

Quality Level

storage temp.

2-8°C

SMILES string

CCCOc1ccc2[nH]c(NC(=O)OC)nc2c1

InChI

1S/C12H15N3O3/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

InChI key

RAOCRURYZCVHMG-UHFFFAOYSA-N

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Biochem/physiol Actions

Anthelminthic

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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G W Lubega et al.
Biochemical pharmacology, 41(1), 93-101 (1991-01-01)
The low- and high-affinity binding of tritiated benzimidazole anthelmintics (mebendazole and oxibendazole) to tubulin-containing supernatants derived from unembryonated eggs, third stage larvae or adult worms of thiabendazole-susceptible and -resistant strains of Haemonchus contortus were examined and compared. The displacement of
A field evaluation of three methods of administration of anthelminthics to horses.
C Uhlinger et al.
Equine veterinary journal, 24(6), 487-488 (1992-11-01)
C Uhlinger et al.
Journal of the American Veterinary Medical Association, 201(1), 51-55 (1992-07-01)
Anthelmintic schedules that alternate between drug classes are widely used in horses. However, the results of investigations in which ovine nematode parasites were used have established that alternation of drug classes does not delay the development of drug resistance. This
S E Bunch
The Veterinary clinics of North America. Small animal practice, 23(3), 659-670 (1993-05-01)
Historical aspects, mechanisms, and treatment of hepatotoxicity associated with pharmacologic agents in dogs and cats are discussed. All agents that cause clinically relevant drug-induced hepatotoxicity have been reviewed within the last 5 years; therefore, only selected drugs that more recently
M R Chapman et al.
Veterinary parasitology, 66(3-4), 205-212 (1996-11-15)
Three fecal egg count reduction assays (FECR) and one critical trial were performed to determine the efficacy of pyrantel pamoate (PP) at 6.6 mg base kg-1 on a well managed stud farm in Louisiana where a loss of efficacy was

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