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700131P

Avanti

24S,27-dihydroxycholesterol

Avanti Research - A Croda Brand 700131P, powder

Synonym(s):

(25S)-cholest-5-en-3β,24S,27-triol

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About This Item

Empirical Formula (Hill Notation):
C27H46O3
CAS Number:
Molecular Weight:
418.65
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (700131P-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 700131P

shipped in

dry ice

storage temp.

−20°C

General description

24S,27-dihydroxycholesterol differs from 24S-hydroxycholesterol in steroid nucleus by having an additional hydroxyl group. 24S,27-dihydroxycholesterol is derived from 24S-hydroxycholesterol in the presence of enzyme cholesterol 24-hydroxylase (P450 46A1).

Packaging

5 mL Amber Glass Screw Cap Vial (700131P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


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Natalia Mast et al.
Biochemistry, 42(48), 14284-14292 (2003-12-03)
The known activity of cytochrome P450 46A1 (P450 46A1) is 24(S)-hydroxylation of cholesterol. This reaction produces biologically active oxysterol, 24(S)-hydroxycholesterol, and is also the first step in enzymatic degradation of cholesterol in the brain. We report here that P450 46A1

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