539470

Proteinase K Inhibitor

Proteinase K Inhibitor is a tetrapeptidyl chloromethyl ketone compound that acts as an active-site-targeting irreversible inhibitor against proteinase K.

• Synonym(s): Proteinase K Inhibitor, MeOSuc-AAPF-CMK
• Empirical Formula (Hill Notation): C₂₆H₃₅ClN₄O₇
• Molecular Weight: 551.03
• UNSPSC Code: 12352202
• NACRES: NA.54

Properties

• Quality Level: 200
• Assay: ≥97% (HPLC)
• form: lyophilized
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated; protect from light
• solubility: DMSO: 3 mg/mL
• shipped in: ambient
• storage temp.: −20°C

Description

General description

A tetrapeptidyl chloromethyl ketone compound that acts as an active-site-targeting irreversible inhibitor against proteinase K (Cat. Nos. 539480, 70663, & 71049). Shown to be more potent than MeOSuc-AAPV-CMK (Cat. Nos. 324745) in preventing the degradation of reverse transcriptase and albumin by proteinase K.

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Sequence

MeOSuc-Ala-Ala-Pro-Phe-CH₂Cl

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 week at -20°C.

Other Notes

Kore, A.R., et al. 2009. Bioorg. Med. Chem. Lett.19, 1296.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable