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00720585

Apigenin 7-glucoside

primary reference standard

Synonym(s):

4′,5,7-Trihydroxyflavone 7-glucoside, Apigenin-7-O-glucoside, Apigetrin, Cosmosiin

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About This Item

Empirical Formula (Hill Notation):
C21H20O10
CAS Number:
578-74-5
Molecular Weight:
432.38
Beilstein:
65669
EC Number:
209-430-5
MDL number:
MFCD00016787
UNSPSC Code:
85151701
PubChem Substance ID:
329747125
NACRES:
NA.24

grade

primary reference standard

Quality Level

100

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

SMILES string

OC[C@H]1O[C@@H](Oc2cc(O)c3C(=O)C=C(Oc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C21H20O10/c22-8-16-18(26)19(27)20(28)21(31-16)29-11-5-12(24)17-13(25)7-14(30-15(17)6-11)9-1-3-10(23)4-2-9/h1-7,16,18-24,26-28H,8H2/t16-,18-,19+,20-,21-/m1/s1

InChI key

KMOUJOKENFFTPU-QNDFHXLGSA-N

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General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Reference Standard in the analysis of herbal medicinal products

Other Notes

This compound is commonly found in plants of the genus: achillea ginkgo humulus hypericum melissa mentha pimpinella plantago salvia silybum thymus

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
HWI00095-4
HWI00095-2
HWI00095-1

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Laura Hanske et al.
The Journal of nutrition, 139(6), 1095-1102 (2009-05-01)
We investigated the impact of human intestinal microbiota on bioavailability of the flavone apigenin-7-glucoside (A7G) by comparing germ-free and human microbiota-associated (HMA) rats. First, the ability of the human intestinal microbiota to convert A7G was proven in vitro by incubating
Zaixing Chen et al.
Archives of pharmacal research, 34(5), 741-746 (2011-06-10)
The present study was designed to validate an analytical method based on HPLC for the quantitative measurement of the Apigenin-7-O-β-D-glucoside (AGL) in rat plasma after intravenous administration. HPLC analysis was done using a C18 column, UV detection at 335 nm
Xing-Qi Tan et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 33(1), 58-60 (2010-06-04)
To study the flavonoids constituents of Trachelospemum jasminoides. The compounds were separated and purified by column chromatography with silica gel, and identified by IR, MS, NMR and 2D-NMR. Six flavonoids were identified as apigenin (I), apigenin 7-O-beta-glucoside (II), apigenin 7-O-beta-neospheroside
Ozlem Baris et al.
Journal of food science, 76(9), T212-T217 (2012-03-16)
Flavonoids, abundant in most of plant species, are widely used in medicine and development studies on phytotherapeutic drugs due to their various biological activities. In the present study, 3 flavonoids, apigenin-7-O-glucoside, apigenin-7-O-rutinoside, and apigenin-7-O-glucuronide, were isolated from Mentha longifolia (L.)
M Sharaf
Natural product research, 22(18), 1620-1623 (2008-12-17)
The ethanolic extract of the seeds of Trifolium alexandrinum afforded a new naturally occurring compound identified as methyl-alpha-glucose. The known compounds quercetin, kaempferol, apigenin 7-O-beta-D-glucoside and the nucleoside xanthosine were also isolated. The isolated compounds were identified by spectroscopic (UV
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