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34127

Supelco

Patulin solution

100 μg/mL in acetonitrile, analytical standard

Synonym(s):

4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one, PAT

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About This Item

Empirical Formula (Hill Notation):
C7H6O4
CAS Number:
Molecular Weight:
154.12
EC Number:
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

SMILES string

OC1OCC=C2OC(=O)C=C12

InChI

1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2

InChI key

ZRWPUFFVAOMMNM-UHFFFAOYSA-N

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General description

Patulin is an important mycotoxin produced by several species of mold, especially within PenicilliumAspergillus and Byssochlamys. It is commonly found in fruits especially apples, pears and grapes.
Patulin is a mycotoxin produced by several mold species. It has been found in fruit, especially apples, fruit juice, cider and stewed fruits. Because of its highly toxic properties, this compound has been the focus of many studies.

Application

Patulin solution may be used as an analytical reference standard for the determination of the analyte in:
  • dried apple rings using high-performance liquid chromatography with diode array detection (HPLC-DAD)(1)
  • fruit juices using high-performance liquid chromatography with diode array detection (HPLC-DAD) and gas chromatography coupled to mass spectrometry (GC-MS)(2)

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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HPLC-DAD method for the determination of patulin in dried apple rings.
Katerere RD, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 19(4), 389-392 (2008)
Eszter Horváth et al.
Acta biologica Hungarica, 63(3), 389-398 (2012-09-12)
The effects of the mycotoxin patulin on the thermodynamics and kinetics of the transition of bovine serum albumin (BSA) in aqueous solution were studied by Differential Scanning Calorimetry and Photoluminescence methods. Results show that in the presence of patulin, the
[Analytical methods for mycotoxins].
Setsuko Tabata
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 53(3), 129-138 (2012-07-14)
Marieke Vansteelandt et al.
Fungal biology, 116(9), 954-961 (2012-09-08)
Genus Penicillium represents an important fungal group regarding to its mycotoxin production. Secondary metabolomes of eight marine-derived strains belonging to subgenera Furcatum and Penicillium were investigated using dereplication by liquid chromatography (LC)-Diode Array Detector (DAD)-mass spectrometry (MS)/MS. Each strain was
H Morales et al.
Letters in applied microbiology, 56(5), 356-360 (2013-02-07)
Interactions between fungi occur when they grow on the same host plant. This is the case of Botrytis cinerea and Penicillium expansum on grape. P. expansum is also responsible for production of the mycotoxin patulin. In this study, the influence of

Protocols

This selective and fast MIP extraction procedure allows trace amounts of patulin to be easily detected in apple juice, with high analyte recovery and reproducibility.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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