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50199

Sigma-Aldrich

Gly-Gly

≥99.5% (NT), BioUltra

Synonym(s):

Diglycine, Glycyl-glycine

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About This Item

Linear Formula:
NH2CH2CONHCH2COOH
CAS Number:
Molecular Weight:
132.12
Beilstein:
1765223
EC Number:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

product name

Gly-Gly, BioUltra, ≥99.5% (NT)

product line

BioUltra

Assay

≥99.5% (NT)

form

powder

impurities

insoluble matter, passes filter test

ign. residue

≤0.05% (as SO4)

loss

≤0.05% loss on drying, 110 °C

color

white

pH

4.5-6.0 (20 °C, 1 M in H2O)

useful pH range

7.5-8.9

pKa (25 °C)

8.2

mp

220-240 °C

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
NH4+: ≤200 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in H2O

UV absorption

λ: 260 nm Amax: 0.075
λ: 280 nm Amax: 0.072

SMILES string

NCC(=O)NCC(O)=O

InChI

1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)

InChI key

YMAWOPBAYDPSLA-UHFFFAOYSA-N

Gene Information

human ... SLC15A1(6564)

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Application

  • Structural and molecular insights into a bifunctional glycoside hydrolase 30 xylanase specific to glucuronoxylan: This study provides a detailed analysis of the enzyme′s structure and function, demonstrating D-(+)-Xylose′s role in enhancing our understanding of xylose metabolism in industrial applications such as biofuel production and biotechnological innovations (Pentari et al., 2024).

  • Efficient production of 1,2,4-butanetriol from corn cob hydrolysate by metabolically engineered Escherichia coli: Highlights the utilization of D-(+)-Xylose from agricultural waste, optimizing processes for sustainable biofuel production, emphasizing the sugar′s pivotal role in renewable energy research (Li et al., 2024).

  • Biochemical characterization of a xylose-tolerant GH43 β-xylosidase from Geobacillus thermodenitrificans: Provides insights into the enzyme′s biophysical properties and its utility in biotechnological applications, furthering the understanding of D-(+)-Xylose′s role in enhancing enzyme performance under various industrial conditions (Melo et al., 2023).

  • Genome-scale metabolic modeling reveals metabolic trade-offs associated with lipid production in Rhodotorula toruloides: Explores how D-(+)-Xylose can be used to optimize metabolic pathways for improved lipid production, highlighting its potential in synthetic biology and metabolic engineering to enhance bioproduct synthesis efficiency (Reķēna et al., 2023).

Other Notes

Superior buffer for the growth of Aphanosthece halophytica (Chroococcales) in hypersaline media

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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P B Armentrout et al.
Journal of the American Society for Mass Spectrometry, 23(4), 621-631 (2011-09-29)
We present a full computational description of the fragmentation reactions of protonated diglycine (H(+)GG). Relaxed potential energy surface scans performed at B3LYP/6-31 G(d) or B3LYP/6-311 + G(d,p) levels are used to map the reaction coordinate surfaces and identify the transition states (TSs) and
Namrata D Udeshi et al.
Molecular & cellular proteomics : MCP, 12(3), 825-831 (2012-12-26)
Detection of endogenous ubiquitination sites by mass spectrometry has dramatically improved with the commercialization of anti-di-glycine remnant (K-ε-GG) antibodies. Here, we describe a number of improvements to the K-ε-GG enrichment workflow, including optimized antibody and peptide input requirements, antibody cross-linking
P B Armentrout et al.
Journal of the American Society for Mass Spectrometry, 23(4), 632-643 (2011-09-29)
We present a full molecular description of fragmentation reactions of protonated diglycine (H(+)GG) by studying their collision-induced dissociation (CID) with Xe using a guided ion beam tandem mass spectrometer (GIBMS). Analysis of the kinetic energy-dependent CID cross sections provides the
Daniel H Haft et al.
PloS one, 6(12), e28886-e28886 (2011-12-24)
The rhomboid family of serine proteases occurs in all domains of life. Its members contain at least six hydrophobic membrane-spanning helices, with an active site serine located deep within the hydrophobic interior of the plasma membrane. The model member GlpG

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