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P1504

Sigma-Aldrich

TWEEN® 40

viscous liquid

Synonym(s):

Polyoxyethylenesorbitan monopalmitate

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About This Item

CAS Number:
9005-66-7
MDL number:
MFCD00165345
UNSPSC Code:
12161900
NACRES:
NA.25

description

non-ionic

Quality Level

200

Assay

~90.0% (GC)

form

viscous liquid

mol wt

estimated mol wt 1277

composition

Palmitic acid, ~90% (balance primarily stearic acid)

technique(s)

DNA extraction: suitable
RNA extraction: suitable
cell culture | mammalian: suitable
protein purification: suitable

CMC

0.027 (20-25°C)

HLB

15.6

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

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General description

Polyoxyethylenesorbitan monopalmitate, or TWEEN 40, is a non-ionic detergent.

Application

Non-ionic detergent used for cell lysis, nuclei isolation and cell fractionation.
Polyoxyethylenesorbitan monopalmitate, or TWEEN 40, has been used in a study to assess the determination of iodide in urine based on a chemiluminescence system. It has also been used in a study to investigate the delivery of astaxanthin and canthaxanthin to HepG2 cells.

Legal Information

TWEEN is a registered trademark of Croda International PLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Determination of iodide in urine based on chemiluminescence system of cerium (IV)-tween 40-iodide
Li and Xie
Journal of Luminescence, 132, 5-5 (2012)
Christine Boesch-Saadatmandi et al.
Cytotechnology, 63(1), 89-97 (2010-12-15)
The present investigation aimed to compare fetal calf serum (FCS) and Tween 40 with the commonly employed tetrahydrofuran (THF) with respect to cytotoxicity, stability of the solubilized carotenoids, and uptake and accumulation of the xanthophylls astaxanthin (AX) and canthaxanthin (CX)
Matija Tomsic et al.
International journal of pharmaceutics, 327(1-2), 170-177 (2006-08-26)
Small-angle X-ray scattering technique has been used to study the structural properties of the quaternary microemulsion Tween 40/Imwitor 308/isopropyl myristate/water and of five-component system obtained by the addition of the drug ketoprofen to the original quaternary system. The results enlighten
Cheng-Yu Liu et al.
Chemical communications (Cambridge, England), 47(9), 2550-2552 (2011-01-11)
This study describes a simple method for the selective and sensitive detection of cyanide and endogenous biological cyanide using polysorbate 40-stabilized gold nanoparticles.
Peter Klauth et al.
Applied microbiology and biotechnology, 72(5), 1099-1106 (2006-09-16)
Corynebacterium glutamicum forms inorganic polyphosphate (poly P) that may occur as soluble (cytosolic) poly P and/or as volutin granules. A suitable method for monitoring soluble and granular poly P in C. glutamicum was developed and applied to C. glutamicum cells
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