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P7780

Sigma-Aldrich

Propionylpromazine hydrochloride

Synonym(s):

Propiopromazine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C20H24N2OS · HCl
CAS Number:
7681-67-6
Molecular Weight:
376.94
Beilstein:
38502
MDL number:
MFCD01941563
UNSPSC Code:
12352200
PubChem Substance ID:
24278651
NACRES:
NA.77

form

powder

storage temp.

2-8°C

SMILES string

Cl.CCC(=O)c1ccc2Sc3ccccc3N(CCCN(C)C)c2c1

InChI

1S/C20H24N2OS.ClH/c1-4-18(23)15-10-11-20-17(14-15)22(13-7-12-21(2)3)16-8-5-6-9-19(16)24-20;/h5-6,8-11,14H,4,7,12-13H2,1-3H3;1H

InChI key

ZFWVWZODBGTOIL-UHFFFAOYSA-N

Gene Information

human ... DRD2(1813)

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Biochem/physiol Actions

Phenothiazine antipsychotic; D2 dopamine receptor antagonist.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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R Langer et al.
Zentralblatt fur Veterinarmedizin. Reihe A, 41(7), 509-522 (1994-09-01)
The effect of Combolen (3.9 mg/kg bw s.c.) on the distribution of erythrocytes in dogs was investigated. After application of Combolen, the hematocrit of the animals decreased exponentially within 1 h by 21%. The reversal of the reduction began from
Y Govaert et al.
The Analyst, 123(12), 2507-2512 (1999-08-06)
A rapid and sensitive multi-residue method was developed to attempt to confirm the presence of the beta-blocker carazolol and the tranquillizers acepromazine, azaperone, chlorpromazine, propionylpromazine and xylazine in pig muscle tissues. The procedure involves determination by liquid chromatography coupled with
[The opinion of O. Habler].
O Habler
Der Anaesthesist, 50(8), 613-614 (2001-09-15)
M Olling et al.
Journal of veterinary pharmacology and therapeutics, 4(4), 291-294 (1981-12-01)
A thin-layer chromatographic method for the determination of the veterinary tranquillizer propiopromazine (Combelen) in slaughter pigs is described. Propiopromazine residue depletion from the kidney occurs with different rates in sows and in castrated boars. In the liver residues increase over
[Acute normovolemic hemodilution (ANH). Der Anaesthesist (2000) 49: 939-948].
M Alef
Der Anaesthesist, 50(8), 612-613 (2001-09-15)
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