901011

Poly(caprolactone-co-glycolide)

40:60, viscosity 1.6 dL/g 

• Synonym(s): PGA-PCL, PGCL
• Linear Formula: (C₄H₄O₄)_m(C₆H₁₀O₂)_n
• UNSPSC Code: 12162002
• NACRES: NA.23

Properties

• form: chips
• feed ratio: glycolide:caprolactone 60:40±5
• color: light yellow to tan
• viscosity: 1.2-2.0 dL/g; 1.6 dL/g
• shipped in: dry ice
• storage temp.: −20°C

Description

General description

Poly(caprolactone-co-glycolide) (PGCL) is a biodegradable and biocompatible copolymer synthesized from the ring opening polymerization of glycolide and ε-caprolactone. Due to the ester linkages found in the polymer backbone, these copolymers are able to degrade via hydrolysis. Depending on the ratio of monomers used and polymer block structure, different forms of PGCL can be obtained. These differing forms yield materials with different degrees of crystallinity, thermal transitions, solubility, and rates of degradation.

Application

Poly(caprolactone-co-glycolide) (PGCL) is a biodegradable and biocompatible copolymer for use in biomedical research devices, such as implants, sutures, prosthetic devices, scaffolds for tissue engineering applications, micro and nanoparticles. PGA-PCL is also utilized in drug delivery research, such as in the synthesis and application of polymer-drug conjugates.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable