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Sigma-Aldrich

BrdU (5-Bromo-2′-deoxyuridine)

Used for the study of DNA synthesis where it is incorporated into DNA in place of thymidine, BrdU can be used in conjunction with anti-BrdU for immunocytochemical analysis of cell proliferation.

Synonym(s):

Bromodeoxyuridine

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About This Item

UNSPSC Code:
41116012
eCl@ss:
32160405
NACRES:
NA.41

Quality Level

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable

shipped in

wet ice

Application

Research Category
All
Used for the study of DNA synthesis where it is incorporated into DNA in place of thymidine; BrdU can be used in conjunction with anti-BrdU for immunocytochemical analysis of cell proliferation.

Physical form

C9H11BrN2O5

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Muta. 1B - Repr. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2


Certificates of Analysis (COA)

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Immunocytochemical detection of S-phase cells in normal and neoplastic cervical epithelium by anti-BrdU monoclonal antibody
Fukuda, K, et al
Analytical and Quantitative Cytology and Histology, 12, 135-138 (1990)
Maduraimuthu Djanaguiraman et al.
ACS omega, 3(10), 14406-14416 (2018-11-10)
Drought is a major abiotic stress affecting crop growth and yield worldwide. Drought-induced oxidative stress results in the reduction of plant photosynthesis and reproductive success. Cerium oxide nanoparticles (nanoceria) possess potent antioxidant properties that can alleviate drought-induced oxidative stress by
Sheng-Hua Ying et al.
Scientific reports, 6, 26376-26376 (2016-05-21)
Autophagy-related proteins play significantly different roles in eukaryotes. In the entomopathogenic fungus Beauveria bassiana, autophagy is associated with fungal growth and development. BbATG1 (a serine/threonine protein kinase) and BbATG8 (a ubiquitin-like protein) have similar roles in autophagy, but different roles
G Cattoretti et al.
The Journal of pathology, 171(2), 83-98 (1993-10-01)
Enzymatic and non-enzymatic treatments for antigen unmasking on formalin-fixed, paraffin-embedded, dewaxed sections were optimized and compared by the use of a panel of antibodies of diagnostic relevance (anti-cytokeratins, vimentin, S-100, T- and B-cell receptors, Ki-67/MIB 1, muscle actin). Non-enzymatic unmasking
Xiaochao Chen et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 107, 286-294 (2016-07-28)
The purpose of this study was to evaluate whether topical application of superoxide dismutase with cell penetrating peptide (HIV-TAT) could protect against skin damage induced by UVB irradiation in humans. The permeability through stratum corneum of large proteins linked to

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