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Key Documents

PP50

Sigma-Aldrich

IgM, Mouse

Mouse IgM Polyclonal Antibody control validated for use in ELISA.

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

clone

polyclonal

manufacturer/tradename

Chemicon®

concentration

2.0 mg/mL

technique(s)

ELISA: suitable

shipped in

wet ice

target post-translational modification

unmodified

General description

Source: Normal mouse serum.

Application

Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Suitable for use as an antigen/ligand in immunochemical reactions, as a control in assays, in conjugation and other immunological methods requiring highly purified immunogloblins.

Quality

Single precipititin arc was observed against anti-mouse whole sera and anti-mouse IgM (μ chain specific) when assayed by IEP. No reaction was observed against anti-mouse IgG (Fc). Some light chain cross-reactivity may occur with anti-mouse IgG (H&L).

Physical form

Format: Purified
Purified immunoglobulin. Liquid (sterile filtered), in 0.1M Tris Chloride, 0.5M NaCl pH 8.0 with 0.1% sodium azide.

Storage and Stability

Maintain at +2-8°C before opening. The product is stable at +2-8°C as an undiluted liquid for up to 12 months after date of receipt before opening. For extended storage mix with an equal volume of glycerol (ACS grade or better), aliquot contents and freeze at -20°C or below for up to 6 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Manabu Kinoshita et al.
Infection and immunity, 79(7), 2670-2680 (2011-05-04)
Methicillin-resistant Staphylococcus aureus (MRSA) infection is a grave concern in burn-injured patients. We investigated the efficacy of interleukin-18 (IL-18) treatment in postburn MRSA infection. Alternate-day injections of IL-18 into burn-injured C57BL/6 mice significantly increased their survival after MRSA infection and
Xianli Wang et al.
Bioscience reports, 31(2), 87-98 (2010-05-11)
HF (heart failure) after MI (myocardial infarction) is a major cause of morbidity and mortality worldwide. Recent studies have shown that hydrogen sulfide (H2S) has cardioprotective effects. Hence, we aimed to elucidate the potential effects of H2S on HF after
Cardiac dysfunction induced by experimental myocardial infarction impairs the host defense response to bacterial infection in mice because of reduced phagocytosis of Kupffer cells.
Nogami Y, Kinoshita M, Takase B, Inatsu A, Ishihara M, Seki S, Maehara T
The Journal of Thoracic and Cardiovascular Surgery null
Dominique Kagele et al.
Virology, 424(2), 106-114 (2012-01-13)
Human cytomegalovirus transient lytic DNA replication relies on the cis-acting element oriLyt, six viral-encoded core proteins, the proposed DNA replication initiator protein UL84, IE2, IRS1 and the gene products from the UL112/113 loci. In an effort to elucidate cellular and
Restoration of natural IgM production from liver B cells by exogenous IL-18 improves the survival of burn-injured mice infected with Pseudomonas aeruginosa.
Manabu Kinoshita, Nariyoshi Shinomiya, Satoshi Ono, Hironori Tsujimoto et al.
Journal of immunology (Baltimore, Md. : 1950) (1950)

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