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434760

Sigma-Aldrich

Benzamidine hydrochloride

99%

Synonym(s):

Amidinobenzene hydrochloride, Benzamidinium chloride

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About This Item

Linear Formula:
C6H5C(=NH)NH2 · HCl
CAS Number:
Molecular Weight:
156.61
Beilstein:
3594959
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

99%

form

beads

mp

169-173 °C (lit.)

solubility

water: soluble

SMILES string

Cl.NC(=N)c1ccccc1

InChI

1S/C7H8N2.ClH/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H3,8,9);1H

InChI key

LZCZIHQBSCVGRD-UHFFFAOYSA-N

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Application

<ul>
<li><strong>Purification and characterization of a serine protease from organic dust and elucidation of its inductive effects on lung i</strong></li>
<li><strong>Preclinical testing of dabigatran in trypsin-dependent pancreatitis:</strong> This research uses Benzamidine hydrochloride to inhibit serine proteases in models of pancreatitis, highlighting its potential in preclinical studies to evaluate new therapeutic approaches for inflammatory and digestive disorders (Pesei et al., 2022).</li>
</ul>

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Zaofeng Yang et al.
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The effectiveness of cancer radiotherapy is frequently hindered by the hypoxia of the tumor microenvironment. Direct delivery of oxygen to hypoxic tumor tissues is an attractive strategy to overcome this hypoxia-associated radioresistance. Herein, we report the generation of submicron-sized particles
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We have recently developed a one-step, genetically encoded immobilization approach based on fusion of a target enzyme to the self-crystallizing protein Cry3Aa, followed by direct production and isolation of the fusion crystals from Bacillus thuringiensis. Using this approach, Bacillus subtilis
Marta M Nowacka-Chmielewska et al.
Pharmacological reports : PR, 69(3), 520-525 (2017-04-01)
Stress is a major predisposing factor in the development of psychiatric disorders and potential source of augmented inflammatory processes in the brain. Increasing body of evidence shows an important role of alterations in the olfactory bulbs (OBs) function in stress-related
Seweryn Mroczek et al.
Nature communications, 8(1), 619-619 (2017-09-22)
FAM46C is one of the most frequently mutated genes in multiple myeloma. Here, using a combination of in vitro and in vivo approaches, we demonstrate that FAM46C encodes an active non-canonical poly(A) polymerase which enhances mRNA stability and gene expression.
Paul S Miller et al.
Nature, 512(7514), 270-275 (2014-06-10)
Type-A γ-aminobutyric acid receptors (GABAARs) are the principal mediators of rapid inhibitory synaptic transmission in the human brain. A decline in GABAAR signalling triggers hyperactive neurological disorders such as insomnia, anxiety and epilepsy. Here we present the first three-dimensional structure

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