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Y0001297

Iopentol

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

5-[Acetyl(2-hydroxy-3-methylpropyl)amino]-N,N′-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide

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About This Item

Empirical Formula (Hill Notation):
C20H28I3N3O9
CAS Number:
89797-00-2
Molecular Weight:
835.16
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

iopentol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C20H28I3N3O9/c1-9(29)26(5-12(32)8-35-2)18-16(22)13(19(33)24-3-10(30)6-27)15(21)14(17(18)23)20(34)25-4-11(31)7-28/h10-12,27-28,30-32H,3-8H2,1-2H3,(H,24,33)(H,25,34)

InChI key

IUNJANQVIJDFTQ-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Iopentol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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P Dewachter et al.
Journal de radiologie, 82(9 Pt 1), 973-977 (2001-10-10)
The etiology of severe reactions following injection of iodinated contrast agents is the subject of controversy. No consensus has been established regarding the management of patients at risk, risk factors and premedication because in most cases published no diagnostic exploration
F Jung et al.
The Journal of invasive cardiology, 11(1), 2-8 (2000-04-04)
This single-center, prospective, randomized, double-blind phase IV study in parallel-group design was carried out to investigate whether either of two different x-ray contrast media (iomeprol 350 or iopentol 350) injected into the axillary artery has any influence on cutaneous microcirculation.
Volkmar Lufft et al.
European radiology, 12(4), 804-809 (2002-04-18)
The aim of this study was to compare renal function between patients with renal angiography and patients with renal angiography and angioplasty (AP) for renal artery stenosis (RAS). Forty-seven patients with suspected RAS were prospectively investigated by digital subtraction angiography
GianCarlo Marenzi et al.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 58(1), 59-64 (2003-01-01)
Acute renal failure (ARF) requiring hemodialysis after percutaneous coronary interventions (PCI) is a serious complication with poor prognosis. Hemodialysis-induced hypotension may have deleterious cardiovascular effects, especially in high-risk patients. Ultrafiltrate removal and simultaneous fluid replacement with a solution similar to
Jiri Trcka et al.
AJR. American journal of roentgenology, 190(3), 666-670 (2008-02-22)
Contrast material is generally well tolerated although approximately 1% of patients who receive low-osmolar nonionic contrast material will develop anaphylaxis symptoms. Because most anaphylactic reactions are mild and nonallergic, clinically mimicking immunoglobulin E (IgE)-mediated allergy, diagnostic skin testing has been
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