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Key Documents

Y0001428

Pheniramine impurity A

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2-Benzylpyridine

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About This Item

Empirical Formula (Hill Notation):
C12H11N
CAS Number:
Molecular Weight:
169.22
Beilstein:
115875
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

pheniramine

manufacturer/tradename

EDQM

refractive index

n20/D 1.579 (lit.)

bp

276 °C (lit.)

mp

8-10 °C (lit.)

density

1.054 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

C(c1ccccc1)c2ccccn2

InChI

1S/C12H11N/c1-2-6-11(7-3-1)10-12-8-4-5-9-13-12/h1-9H,10H2

InChI key

PCFUWBOSXMKGIP-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Pheniramine impurity A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

257.0 °F - closed cup

Flash Point(C)

125 °C - closed cup


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Masaki Itoh et al.
Organic letters, 16(7), 2050-2053 (2014-03-22)
The direct α-methylenation of benzylpyridines was achieved using N,N-dimethylacetamide (DMA) as a one-carbon source under copper catalysis. An intermediary species was detected at an early stage, and a possible mechanism was proposed. Additionally, α-oxygenation and dimerization of benzylpyridines could also

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