360554

Nitromethane

ACS reagent, ≥95%

• Empirical Formula (Hill Notation): CH₃NO₂
• CAS Number: 75-52-5
• Molecular Weight: 61.04
• Beilstein: 1698205
• EC Number: 200-876-6
• MDL number: MFCD00007400
• UNSPSC Code: 12352102
• PubChem Substance ID: 329755264
• NACRES: NA.21

Properties

• grade: ACS reagent
• Quality Level: 200
• vapor density: 2.1 (vs air)
• vapor pressure: 2.7 mmHg ( 20 °C)
• Assay: ≥95%
• form: liquid
• autoignition temp.: 784 °F
• expl. lim.: 7.3 %, 33 °F
• impurities: ≤0.05% water
• color: APHA: ≤10
• refractive index: n20/D 1.382 (lit.)
• pH: 6.4 (20 °C, 0.01 g/L)
• bp: 101.2 °C (lit.)
• mp: −29 °C (lit.)
• density: 1.127 g/mL at 25 °C (lit.)
• suitability: clear for appearance
• SMILES string: C[N+]([O-])=O
• InChI: 1S/CH3NO2/c1-2(3)4/h1H3
• InChI key: LYGJENNIWJXYER-UHFFFAOYSA-N

Description

General description

Nitromethane is an aliphatic nitro compound that is commonly used as a solvent for chemical processing and analysis.

Application

Nitromethane can be used as a solvent in the:

• FeCl₃-catalyzed Friedel-Crafts alkylation of indoles with alcohols.
• Cobalt-catalyzed dehydration of aldoximes to nitriles.
• Chemoselective oxidation of alcohols to carbonyl compounds.
• Gold-catalyzed hydroarylation of aryl-substituted alkynes.

Safety Information

• Pictograms: GHS02,GHS08,GHS07
• Signal Word: Warning
• Hazard Statements: H226,H302 + H332,H351,H361d
• Precautionary Statements: P202 - P210 - P233 - P301 + P312 - P304 + P340 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Flam. Liq. 3 - Repr. 2
• Storage Class Code: 4.1A - Other explosive hazardous materials
• WGK: WGK 2
• Flash Point(F): 95.0 °F - closed cup
• Flash Point(C): 35 °C - closed cup