C1288

Complement C6 deficient serum human

for complement assays

• UNSPSC Code: 12352202
• NACRES: NA.61

Properties

• biological source: human
• Quality Level: 200
• form: liquid
• technique(s): activity assay: suitable
• UniProt accession no.: P13671
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... C6(729)

Description

Application

Complement C6 is one of the end terminals of the complement system contained in the membrane attack complex (MAC). A deficiency of C6 may result in an increased susceptibility to Neisseria meningitidis. Research has identified that a mutation which leads to a 31 bp deletion in exon 10 in the C6 gene results in C6 deficiency. A coagulation defect has also been observed in mice that are C6 deficient.

Physical form

Supplied as a solution in PBS, pH 7.4

Analysis Note

C6 is depleted by immunoadsorption as judged by a highly sensitive hemolytic assay.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable