P2191

Poly(D,L-lactide-co-glycolide)

lactide:glycolide (50:50), mol wt 30,000-60,000

• Synonym(s): LACTEL^® B6010-2, PLGA
• Linear Formula: [C₃H₄O₂]_x[C₂H₂O₂]_y
• MDL number: MFCD00131930
• UNSPSC Code: 12352211
• PubChem Substance ID: 24898286
• NACRES: NA.25

Properties

• feed ratio: lactide:glycolide (50:50)
• mol wt: 30,000-60,000
• storage temp.: −20°C
• SMILES string: OCC(O)=O.CC(O)C(O)=O

Description

General description

Poly(D,L-lactide-co-glycolide) is a biodegradable and biocompatible polymer, which is used for drug delivery. It is used to treat rheumatoid arthritis, ulcerative colitis, Crohn′s disease, inflammatory lung diseases and ophthalmic inflammatory disorders. Poly(D,L-lactide-co-glycolide) functions as a potential cancer therapeutic target.

Application

Poly(D,L-lactide-co-glycolide) has been used to raise and sustain an increased lactate monomer level in the gel at a concentration relevant to dermal wounds.

Features and Benefits

Controlled release of bioactive agents, sutures and bioabsorbable implantable devices.

Physical form

Biocompatible, biodegradable polymer.

Legal Information

Lactel is a registered trademark of Evonik Corp

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves