S4521
Saponin from Quillaja sp.
Sapogenin content 20-35 %
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description
non-ionic
composition
Sapogenin content, 20-35%
technique(s)
HPLC: suitable
protein quantification: suitable
sulfated ash
≤10%
General description
Saponins are steroid or triterpenoid glycosides. They are biosurfactants that have several uses in the food and cosmetic industry.
Application
Saponin from Quillaja bark has been used:
- to stain fertilized oocytes
- in the analysis of intracellular cytokine production
- to permeabilize dendritic cells
Biochem/physiol Actions
Saponins solubilize the low density lipoprotein (LDL) fraction of cholesterol in micelles, thus lowering their concentration. Saponin from Quillaja bark is used as a flavoring agent in food and beverages. This saponin has been shown to enhance immune-cell proliferation in vitro.
Potent hemolytic when injected i.v.; surfactant that enhances penetration of proteins and other macromolecules through cell membranes; it also has been used as an adjuvant for vaccines.
Preparation Note
Purified to remove low molecular weight contaminants
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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