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Key Documents

SMB01048

Sigma-Aldrich

Uzarin

≥90% (LC/MS-ELSD)

Synonym(s):

(3beta,5alpha)-3-((6-O-beta-D -glucopyranosyl-beta-D -glucopyranosyl)oxy)-14-hydroxycard-20(22)-enolide, Uzarigenin 3-β-sophoroside

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About This Item

Empirical Formula (Hill Notation):
C35H54O14
CAS Number:
Molecular Weight:
698.79
UNSPSC Code:
12352205
NACRES:
NA.25

biological source

plant

Assay

≥90% (LC/MS-ELSD)

form

solid

mol wt

698.79

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

InChI

1S/C35H54O14/c1-33-8-5-18(46-32-30(28(42)26(40)23(14-37)48-32)49-31-29(43)27(41)25(39)22(13-36)47-31)12-17(33)3-4-21-20(33)6-9-34(2)19(7-10-35(21,34)44)16-11-24(38)45-15-16/h11,17-23,25-32,36-37,39-44H,3-10,12-15H2,1-2H3/t17-,18-,19+,20-,21+,22+,23+,25+,26+,27-,28-,29+,30+,31-,32+,33-,34+,35-/m0/s1

InChI key

RIPMDUQTRRLJTE-QHYHXNCWSA-N

General description

Uzarin, also known as Uzarigenin, is a cardenolide glycoside commonly found in plants such as Xysmalobium undulatum, Nerium oleander, Asclepias fruticosa, and Calotropis procera. Existing research suggests that this plant-derived metabolite exerts multiple biological properties, including antidiarrheal, antiviral and anticancer.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

According to the existing research, Uzarin plays potential role as an inhibitor of the SARS-CoV-2 receptor binding domain and SARS-CoV-2 RNA-dependent polymerase, as indicated by molecular docking and dynamics studies.

Features and Benefits

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - STOT RE 2

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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