SML1647

Epiblastin A

≥98% (HPLC)

• Synonym(s): 2,4,7-Triamino-6-(m-chlorophenyl)-pteridine, 6-(3-Chlorophenyl)-2,4,7-pteridinetriamine
• Empirical Formula (Hill Notation): C₁₂H₁₀ClN₇
• CAS Number: 16470-02-3
• Molecular Weight: 287.71
• MDL number: MFCD02947161
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825988
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to light brown
• solubility: DMSO: 1 mg/mL, clear (warmed)
• storage temp.: room temp
• SMILES string: NC1=NC(N)=C2C(N=C(N)C(C3=CC=CC(Cl)=C3)=N2)=N1
• InChI: 1S/C12H10ClN7/c13-6-3-1-2-5(4-6)7-9(14)18-11-8(17-7)10(15)19-12(16)20-11/h1-4H,(H6,14,15,16,18,19,20)
• InChI key: ZWNKKZSRANLVEW-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Epiblastin A is triamterene derivative that potently induces reprograming of epiblast stem cells (EpiSC) into embryonic stem cells (ESC). Epiblastin A is a potent reversible inhibitor of casein kinase 1 (CK1) α, δ, and ε that binds to ATP-binding site.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable