533203
2-(2-Hydroxy-5-methylphenyl)benzotriazole
97%
Synonym(s):
2-(2H-Benzotriazol-2-yl)-p-cresol
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About This Item
Empirical Formula (Hill Notation):
C13H11N3O
CAS Number:
Molecular Weight:
225.25
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
97%
reaction suitability
reaction type: C-C Bond Formation
mp
125.5-129.5 °C (lit.)
SMILES string
Cc1ccc(O)c(c1)-n2nc3ccccc3n2
InChI
1S/C13H11N3O/c1-9-6-7-13(17)12(8-9)16-14-10-4-2-3-5-11(10)15-16/h2-8,17H,1H3
InChI key
MCPKSFINULVDNX-UHFFFAOYSA-N
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Related Categories
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 1 - Skin Sens. 1B
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Contact allergy to Tinuvin P.
A C de Groot et al.
Contact dermatitis, 9(4), 324-325 (1983-07-01)
Hiroshi Tokunaga et al.
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences, (120)(120), 98-100 (2003-03-18)
2-(2'-hydroxy-5'-methylphenyl)-benzotriazole (HMB) is nominated as the restricted ingredients in cosmetics in Japanese Pharmaceutical Affairs Act. So the analytical method for HMB was investigated by HPLC. After dissolving HMB in cream or oil with tetrahydrofuran and making the constant volume with
Y Ikarashi et al.
Contact dermatitis, 30(4), 226-230 (1994-04-01)
The contact sensitizing potential of 2-(2'-hydroxy-5'-methylphenyl)benzotriazole (Tinuvin P) was investigated using the murine local lymph node assay (LLNA) and the mouse ear swelling test with some modification in the induction procedure (modified MEST). Topical exposure of the ears to Tinuvin
Rosa María Claramunt et al.
Molecules (Basel, Switzerland), 12(9), 2201-2214 (2007-10-27)
2-(2,4-Dimethylphenyl)-2H-benzotriazole (1) has been synthesized in a three step procedure starting from 2,4-dimethyl-N-(2-nitrophenyl)benzamide via a 5-(2,4- dimethylphenyl)-1-(2-nitrophenyl)-1H-tetrazole intermediate. Its structure and those of Tinuvin P and 2-phenyl-2H-benzotriazole (5) have been studied by multinuclear NMR (1H-, 13C- and 15N-) in solution
B Björkner et al.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society, 8(1), 6-7 (1997-03-01)
A case of contact allergy to the UV absorber Tinuvin P is described in a patient with gingivitis who was previously treated with a dental restorative material. With high-performance liquid chromatography analysis, the presence of Tinuvin P could be shown
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