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species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type plasma
sample type serum
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.82 ng/mL
standard curve range: 0.819-200 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... MB(4151)
General description
The MB ELISA kit provides for the Quantitative measurement of Myoglobin in Cell Culture Supernatants, Plasma and Serum.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Myoglobin is a hemoprotein that regulates the storage and diffusion of oxygen in heart and skeletal muscles. It also protects the tissues from oxidative damage by controlling the levels of reactive oxygen species and nitric oxide. Myoglobin modulates nitric oxide and oxygen levels in the mitochondrial compartments of skeletal muscle and cardiac cells.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Kapil Kumar Gupta et al.
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Endoplasmic reticulum (ER) stress-induced apoptosis is a major cause of myocardial ischemia/reperfusion (I/R) injury. Emerging evidence indicates that glucagon-like peptide-1 (GLP-1) has potential cardioprotective effects. However, the precise mechanisms underlying the involvement of GLP-1 in I/R injury remain largely unknown.
May N Bin-Jumah
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Hypercholesterolemia is a metabolic disorder associated with oxidative stress. The present study investigated the protective effect of Monolluma quadrangula extract on hypercholesterolemia-induced oxidative stress in the liver and heart of high-cholesterol-diet- (HCD-) fed rats. The experimental animals received HCD for
Myoglobin: an essential hemoprotein in striated muscle.
Ordway GA, et al.
The Journal of Experimental Biology, 207(20), 3441-3446 (2004)
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