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Merck

CCL5

chemokine (C-C motif) ligand 5

Sinonimi:
D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP
Specie:
Human CCL5 (6352), Mouse Ccl5 (20304), Rat Ccl5 (81780), sheep CCL5 (101115553), domestic guinea pig Ccl5 (100135495), naked mole-rat Ccl5 (101712384), chicken CCL5 (417465), cow CCL5 (327712), Horse CCL5 (100033925), domestic cat CCL5 (493689)
ID UniProtKB:
P13501, O43646, Q0QVW8, Q4ZGJ1, Q9NYA2, Q9UBG2, Q9UC99
ID gene:
  • Human(6352) Summary: This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of two N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
  • Mouse(20304) chemokine (C-C motif) ligand 5
  • Rat(81780) chemokine (C-C motif) ligand 5
  • sheep(101115553) chemokine (C-C motif) ligand 5
  • domestic guinea pig(100135495) chemokine (C-C motif) ligand 5
  • naked mole-rat(101712384) chemokine (C-C motif) ligand 5
  • chicken(417465) chemokine (C-C motif) ligand 5
  • cow(327712) chemokine (C-C motif) ligand 5
  • Horse(100033925) chemokine (C-C motif) ligand 5
  • domestic cat(493689) chemokine (C-C motif) ligand 5
  • dog(403522) chemokine (C-C motif) ligand 5

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ELISA

Numero di prodotto
Descrizione
Specie
RAB0076
Human RANTES / CCL5 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Specie
human
RAB0077
Mouse RANTES / CCL5 ELISA Kit, for serum, plasma and cell culture supernatant,
Specie
mouse
RAB0527
Feline CCL5 / C-C Motif Chemokine 5 ELISA Kit, for serum, plasma and cell culture supernatants,
Specie
domestic cat
RAB1827
Rhesus Macaque RANTES ELISA, for serum, plasma and cell culture supernatants,
Specie

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
R9400
Monoclonal Anti-RANTES antibody produced in rat, clone 53405.111, purified immunoglobulin, lyophilized powder,
Reattività con
mouse
Applicazione
immunocytochemistry
neutralization
MABF3184
Anti-RANTES/CCL5 Antibody, clone 15B5.6, ,
Reattività con
human
Applicazione
immunohistochemistry
western blot
ZRB2554
Anti-RANTES Antibody, clone 1K17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, monkey, rat
Applicazione
affinity binding assay
flow cytometry
immunohistochemistry
western blot
R125
Anti-RANTES antibody produced in goat, affinity isolated antibody, lyophilized powder,
Reattività con
human
Applicazione
immunohistochemistry
neutralization
western blot

Proteins

Numero di prodotto
Descrizione
Specie
R6267
RANTES human, ≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Specie
human
SRP3269
RANTES human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
EHU120731
MISSION® esiRNA, targeting human CCL5,
Specie
human