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Safety Information

139114

Sigma-Aldrich

(−)-Borneol

predominantly endo, 97%

Synonym(s):

endo-(1S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol

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About This Item

Empirical Formula (Hill Notation):
C10H18O
CAS Number:
464-45-9
Molecular Weight:
154.25
Beilstein:
2038053
EC Number:
207-353-1
MDL number:
MFCD00003759
UNSPSC Code:
12352212
PubChem Substance ID:
24848391
NACRES:
NA.22

vapor density

5.31 (vs air)

Quality Level

100

vapor pressure

33.5 mmHg ( 25 °C)

Assay

97%

form

solid

optical activity

[α]20/D −35.3°, c = 5 in ethanol

bp

210 °C (lit.)

mp

206-208 °C (lit.)

functional group

hydroxyl

SMILES string

[H][C@]12CC[C@](C)([C@H](O)C1)C2(C)C

InChI

1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m0/s1

InChI key

DTGKSKDOIYIVQL-QXFUBDJGSA-N

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General description

(-)-Borneol is a bicyclic monoterpene found in essential oils.

Application

(-)-Borneol has been used to study its antiapoptotic, antioxidative and neuroprotective effect in human neuroblastoma cells (SH-SY5Y).

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Warning

Hazard Statements

H228,H317,H412

Hazard Classifications

Aquatic Chronic 3 - Flam. Sol. 2 - Skin Sens. 1

Storage Class Code

4.1B - Flammable solid hazardous materials

WGK

WGK 2

Flash Point(F)

150.8 °F

Flash Point(C)

66 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

139114-VAR:
139114-100G:
139114-500G:
139114-BULK:
139114-25G:

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Certificates of Analysis (COA)

Lot/Batch Number
STBK1979
STBJ9364
STBH6980
STBG2379V
STBF3146V

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(+)-And (-)-borneol: efficacious positive modulators of GABA action at human recombinant a 1 ? 2 ? 2L GABA A receptors.
Granger RE, et al.
Biochemical Pharmacology, 69(7), 1101-1111 (2005)
Jing-yi Zhao et al.
Journal of Zhejiang University. Science. B, 13(12), 990-996 (2012-12-12)
Borneol, a monoterpenoid alcohol, is used widely, particularly in combined formulas for preventing and curing cardiovascular and cerebrovascular diseases in traditional Chinese medicine. In order to understand the blood and brain pharmacokinetics after intravenous, intranasal, or oral administration and to
Xiao-Hong Wei et al.
Microcirculation (New York, N.Y. : 1994), 20(1), 17-29 (2012-08-24)
The present study was designed to evaluate whether CP was beneficial in alleviating myocardial fibrosis following I/R injury. Sprague-Dawley rats were subjected to 30 minutes occlusion of the LADCA, followed by reperfusion. CP (0.4 or 0.8 g/kg) was daily administered starting from
Xiao Song et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(18), 2489-2492 (2012-01-20)
To investigate the absorption characteristic of borneol. Using single pass perfusion model, the active ingredient of borneol were detected by GC. The drug concentration, perfusion rate and pH value on the absorption of borneol were studied. Perfusion rate on the
Na Zhang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(22), 3180-3183 (2012-03-02)
To research the content changes of excitatory neurotransmitter and inhibitory neurotransmitter in corpus striatum of rats after single-used borneol and combining it with diazepam in hope of comprehending the activity of borneol on central nervous system and to observe whether
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