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Safety Information

220892

Sigma-Aldrich

1,4-Butanediol diglycidyl ether

≥95%

Synonym(s):

1,4-Bis(2,3-epoxypropyloxy)butane

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About This Item

Empirical Formula (Hill Notation):
C10H18O4
CAS Number:
2425-79-8
Molecular Weight:
202.25
Beilstein:
115238
EC Number:
219-371-7
MDL number:
MFCD00005146
UNSPSC Code:
12162002
PubChem Substance ID:
24853198
NACRES:
NA.23

vapor pressure

~10 mmHg ( 20 °C)

Quality Level

200

Assay

≥95%

form

liquid

refractive index

n20/D 1.453 (lit.)

bp

266 °C (lit.)

density

1.1 g/mL at 25 °C (lit.)

SMILES string

C(CCOCC1CO1)COCC2CO2

InChI

1S/C10H18O4/c1(3-11-5-9-7-13-9)2-4-12-6-10-8-14-10/h9-10H,1-8H2

InChI key

SHKUUQIDMUMQQK-UHFFFAOYSA-N

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General description

1,4-Butanediol diglycidyl ether (BDDE) is a viscous liquid , which is hygroscopic in nature. BDDE is the most commonly used homobifunctional epoxide compound. BDDE may react with amines, hydroxyls, sulfhydryl groups to produce secondary amines, ether or thioether bonds respectively.

Application

BDDE is a cross linking agent used
  • for preparing amylose, xylan and hydroxyethyl-cellulose
  • to cross link polyethylenimine which also serves as a hole-blocking layer in organic solar cells
  • to cross link hyaluronic acid into hydrogels
  • for the activation of soluble dextran polymers.
  • Amine or hydroxyl containing bis-epoxy supports are reacted with BDDE to form particles containing terminal epoxide group for immobilization reactions.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Type 3 petroleums
Hazardous rank III
Water soluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

220892-1KG:
220892-50G:
220892-5KG:
220892-BULK:
220892-VAR:
220892-250G:
220892-RSAMPLE:
220892-10G:

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF3318V
MKCV7450
MKCW4374
WXBF4325V
MKCW3375

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Lennart Kenne et al.
Carbohydrate polymers, 91(1), 410-418 (2012-10-10)
Definitions and methods for the quantification of degree of modification and cross-linking in cross-linked hyaluronic acid (HA) hydrogels are outlined. A novel method is presented in which the HA hydrogel is degraded by the enzyme chondroitinase AC and the digest
Yasemin Udum et al.
Organic electronics, 15(5), 997-1001 (2014-05-13)
We have developed a hole-blocking layer for bulk-heterojunction solar cells based on cross-linked polyethylenimine (PEI). We tested five different ether-based cross-linkers and found that all of them give comparable solar cell efficiencies. The initial idea that a cross-linked layer is
Wei-Yao Chen et al.
Materials (Basel, Switzerland), 14(16) (2021-08-28)
(1) Background: Obesity is one of the most widespread chronic diseases and increases the risk of several other chronic diseases, especially type 2 diabetes. (2) Methods: Endobarrier is a new medical device what is worn in the small intestines for
Laura Oakey et al.
Analytical biochemistry, 335(2), 316-325 (2004-11-24)
This study reevaluates the potential for direct coupling of NAD(P)(+) to a carboxylate-terminating spacer arm using carbodiimide-promoted coupling in an attempt to develop a greatly simplified synthetic method for cofactor immobilization that would support the more widespread adoption of kinetic-based
Anabela Alves et al.
International journal of pharmaceutics, 426(1-2), 76-81 (2012-01-28)
The polysaccharide ulvan, composed of sulphated rhamnose, glucoronic and iduronic acids was used to produce polymeric membranes by solvent casting. As ulvan is soluble in water, a cross-linking step was necessary to render the membrane insoluble in water and stable
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